Results 251 to 260 of about 297,091 (301)

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Real-world safety of difelikefalin for chronic kidney disease-associated pruritus: initial insights from a European managed access programme. [PDF]

Clin Kidney J
Latus J, Mayer G, Narvaez C, Manu M, Jesus S, Ruessmann D, Manenti L.   +6 more
europepmc   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

Advanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa, Jingjun Mo, Xiaotong Diao, Feng Xie, Tingting Wang, Haowen Zhao, Dalei Wu, Rolf Müller, Chengzhang Fu   +8 more
wiley   +1 more source

Challenges and needs among pediatric oncology providers in caring for pediatric brain tumor patients and survivors: A qualitative study. [PDF]

Int J Clin Health Psychol
Lefebvre C, Gazzo G, Defachelles AS, El Hakim C, Mezloy-Destracque M, Desjardins L, Entz-Werlé N, Raimbault S, Gehin W, Lamore K.   +9 more
europepmc   +1 more source

Caring in Context: Development of a Family-Centred and Cross-Sectoral Framework to Support Young Carers. [PDF]

Healthcare (Basel)
Frech M, Nagl-Cupal M, Kaiser S, Spittel AM.   +3 more
europepmc   +1 more source

Russian full-scale invasion of Ukraine: epidemiological challenges for public health. [PDF]

BMJ Glob Health
Chumachenko D, Chumachenko T.
europepmc   +1 more source

The process of overcoming challenges faced by midwives providing perinatal mental health care in obstetric facilities in Okinawa, Japan: A qualitative study. [PDF]

Jpn J Nurs Sci
Shimonaka H, Inoue M, Shinjo M, Kobayashi J.   +3 more
europepmc   +1 more source

Management of Chronic Health Situations. [PDF]

Healthcare (Basel)
Sousa L, Käppler C, Faleiros F, Alburquerque G, José H.   +4 more
europepmc   +1 more source

Time to act: climate change and its impacts on women's sexual and reproductive health. [PDF]

Rev Bras Ginecol Obstet
Surita FG, Sánchez ODR, da Mata JAL.
europepmc   +1 more source