Results 111 to 120 of about 53,984 (288)

Comparison of Parametric Rate Models for Gap Times Between Recurrent Events

Mathematics
Over the past two decades, substantial efforts have been made to develop survival models for gap times between recurrent events. An emerging approach involves considering rate models derived from a non-homogeneous Poisson process, thus allowing the ...
Ivo Sousa-Ferreira, Ana Maria Abreu, Cristina Rocha   +2 more
doaj   +1 more source

Intraspecific variation of cochlear morphology in bowhead and beluga whales

The Anatomical Record, EarlyView.
Abstract The bony labyrinth of the petrosal bone, a distinctive feature of mammal skulls, is often identified in micro‐computed tomography imaging to infer species' physiological and ecological traits. When done as part of a comparative study, one individual specimen is normally considered representative of a species, and intraspecific variation is ...
John Peacock, J. G. M. Thewissen
wiley   +1 more source

Automated Diffuser Shape Optimization based on CFD Simulations and Surrogate Modeling

Journal of Applied Fluid Mechanics, 2016
An approach for the optimization of laminar flow in diffusers is presented. The goal in our optimization process is to maximize diffuser performance and, in this way, pressure recovery by optimizing the geometry.
Mostafa Dehghani, Hossein Ajam, Said Farahat   +2 more
doaj  

Bezier curve conjugation for smooth curve joining and corner rounding

Омский научный вестник
The authors propose an analytical method for the smooth connection of two Bezier curves of arbitrary degree using a connecting curve, which is also a Bezier curve.
O. V. Krivosheev, S. V. Mavrin, A. S. Starkova   +2 more
doaj   +1 more source

Origin, evolution and biogeographic dynamics of the European rabbit (Oryctolagus cuniculus) in Southwestern Europe

The Anatomical Record, EarlyView.
Abstract The Pleistocene is a key period for understanding the evolutionary history and palaeobiogeography of the European rabbit (Oryctolagus cuniculus). The species was first documented in southeastern Iberia at the beginning of the Middle Pleistocene and appears to have rapidly spread throughout Southwestern Europe, where it was found in numerous ...
Maxime Pelletier
wiley   +1 more source

Immunologic Profiling Suggests an Association Between Treg Cell Dysfunction and Pain in Knee Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective Pain is the hallmark symptom of osteoarthritis (OA), and its biologic drivers remain poorly understood. Although the role of innate immunity in OA has been extensively studied, the involvement of adaptive immunity, in particular Treg cells, is not well understood.
Marie Binvignat, Johanna Dubois, Maria Marco Salvador, Paul Stys, Fabien Pitoiset, Alexandra Roux, Michèle Sastre, Signe Hassler, Roberta Lorenzon, Claire Ribet, Vanessa Mhanna, Hélène Vantomme, Leslie Adda, Pierre Barennes, Nicolas Coatnoan, Kenz Le Gouge, Caroline Aheng, Alice Courties, Lise Minssen, Atul J. Butte, Adrien Six, Michelle Rosenzwajg, Nicolas Tchitchek, Francis Berenbaum, David Klatzmann, Encarnita Mariotti‐Ferrandiz, Jérémie Sellam   +26 more
wiley   +1 more source

Model‐informed precision dosing of carboplatin in cancer patients by leveraging myelosuppression data from electronic health records

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This study aimed to develop and validate a population pharmacokinetic‐pharmacodynamic (pop‐PK‐PD) model to describe carboplatin‐induced myelosuppression in cancer patients and support dose individualization. Methods Data from 580 cancer patients treated with carboplatin at Amsterdam UMC between 2019 and 2022 were used for model ...
Alessandro De Carlo, Elena Maria Tosca, Mirjam Crul, Tim Schutte, Lia van Zuijlen, Idris Bahce, Medhat M. Said, Jan Buter, Harmen Huls, Paolo Magni, Imke Bartelink   +10 more
wiley   +1 more source

Step selection functions with non‐linear and random effects

Methods in Ecology and Evolution
Step selection functions (SSFs) are used to jointly describe animal movement patterns and habitat preferences. Recent work has extended this framework to model inter‐individual differences, account for unexplained structure in animals' space use and ...
Natasha J. Klappstein, Théo Michelot, John Fieberg, Eric J. Pedersen, Joanna Mills Flemming   +4 more
doaj   +1 more source

3D modeling of salt domes according to detailed drilling data in the Precaspian region

Georesursy
To create three-dimensional models of arcomorph structures based on detailed data of drilling without involving genetic considerations and indirect information, the potential fields method is effective, which consists of finding an approximating three ...
V. V. Lapkovsky, B. V. Lunev, M. P. Antipov, Yu. A. Volozh, Yu. A. Pisarenko, V. V. Fomina   +5 more
doaj   +1 more source

Completion vs. early discontinuation of chemotherapy and the impact on 5‐year all‐cause mortality in women treated for early‐stage breast cancer from 2015 to 2020: A cohort study using a target trial emulation approach

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Chemotherapy is given for early‐stage breast cancer; however, some patients discontinue before completing all planned cycles. This study investigated the impact of early chemotherapy discontinuation on treatment outcomes. Methods This retrospective cohort study used a target trial emulation framework to conduct a causal analysis of the all‐
Luke Steventon, Chengsheng Ju, Kenneth K. C. Man, Rebecca Roylance, Diego Ottaviani, Chiara Creed, Michal Sladkowski, Alec Wisner, Li Wei, Pinkie Chambers   +9 more
wiley   +1 more source