Results 171 to 180 of about 1,164,136 (338)

Microbial Pathogens Implicated in Reproductive Health Infections in a Special Treatment Clinic in Ibadan, Nigeria

open access: yesJournal of Family and Reproductive Health, 2009
Objective: The lack of adequate recognition of health importance of non-HIV reproductive health infections (RHIs) in Nigeria has led into this study, which was to determine clinical pathogens in non-HIV RHI in Nigeria using a tertiary health facility as ...
Adenike Ogunshe   +2 more
doaj  

A General Approach to Relaxing Unconfoundedness [PDF]

open access: yesarXiv
This paper defines a general class of relaxations of the unconfoundedness assumption. This class includes several previous approaches as special cases, including the marginal sensitivity model of Tan (2006). This class therefore allows us to precisely compare and contrast these previously disparate relaxations.
arxiv  

Inference for Treatment Effects Conditional on Generalized Principal Strata using Instrumental Variables [PDF]

open access: yesarXiv
In a setting with a multi-valued outcome, treatment and instrument, this paper considers the problem of inference for a general class of treatment effect parameters. The class of parameters considered are those that can be expressed as the expectation of a function of the response type conditional on a generalized principal stratum.
arxiv  

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

open access: yesFEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy   +14 more
wiley   +1 more source

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

open access: yesFEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang   +7 more
wiley   +1 more source

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