Results 51 to 60 of about 1,164,136 (338)

Using Multiple Pre-treatment Periods to Improve Difference-in-Differences and Staggered Adoption Design [PDF]

arXiv, 2021
While a difference-in-differences (DID) design was originally developed with one pre- and one post-treatment period, data from additional pre-treatment periods are often available. How can researchers improve the DID design with such multiple pre-treatment periods under what conditions?
arxiv  

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Special Issue: Treatments for Fungal Infections [PDF]

Journal of Fungi, 2018
Antifungal therapy is complicated compared to antibacterial treatments by the fact that fungi and their hosts are both eukaryotic organisms, resulting in fewer targets for selective activity. [...]
Daniel Elad, Esther Segal
openaire   +3 more sources

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

SPECIAL TREATMENT INTERDICIPLINARY JOURNAL, 2023. Vol. 9. (1.)

Különleges Bánásmód, 2023
Special Treatment Journal, 2023. Vol. 9.
Bánásmód Folyóirat Különleges
doaj   +1 more source

Synthetic Blip Effects: Generalizing Synthetic Controls for the Dynamic Treatment Regime [PDF]

arXiv, 2022
We propose a generalization of the synthetic control and synthetic interventions methodology to the dynamic treatment regime. We consider the estimation of unit-specific treatment effects from panel data collected via a dynamic treatment regime and in the presence of unobserved confounding.
arxiv  

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

The Impact of COVID-19 on the Language Skills of Preschool Children: Data from a School Screening Project for Language Disorders in Greece

Children
Background/Objectives: The COVID-19 pandemic has significantly affected children’s lives, particularly preschool-aged children who undergo rapid biological and psychosocial development. This study aimed to investigate the effects of the COVID-19 pandemic
Eleni Kyvrakidou, Giannis Kyvrakidis, Anastasia S. Stefanaki, Asterios Asimenios, Athanasios Gazanis, Asterios Kampouras   +5 more
doaj   +1 more source

Associations between cardiovascular risk factors, disease activity and cardiorespiratory fitness in patients with inflammatory joint disease: a cross-sectional analysis

BMC Sports Science, Medicine and Rehabilitation, 2023
Background Inflammatory joint diseases (IJD) are accompanied by an increased risk of cardiovascular disease (CVD). Cardiorespiratory fitness (CRF) is a modifiable CVD risk factor and low levels of CRF associate with an elevated CVD risk. This study aimed
Kristine Røren Nordén, Anne Grete Semb, Hanne Dagfinrud, Jonny Hisdal, Sigrid Ødegård, Joseph Sexton, Camilla Fongen, Jon Skandsen, Thalita Blanck, George S. Metsios, Anne Therese Tveter   +10 more
doaj   +1 more source

Treatment algorithms for special cases

TURKDERM, 2022
Treatment of psoriasis differs in special cases such as in women who wish to become pregnant, during pregnancy and lactation, in pediatric and geriatric populations, in the presence of obesity or chronic viral diseases, and during the COVID-19 pandemic.
openaire   +3 more sources