Results 121 to 130 of about 61,817 (298)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Special Cycles on GSpin Shimura Varieties [PDF]
, 2019 In this thesis we prove that a certain generating function of special cycles on GSpin Shimura varieties is modular. More specifically, we consider the Shimura variety corresponding to the reductive group $\Res_{F/\Q} G$, where $G=\GSpin(V)$ the GSpin ...
Yott, Dylan Taylor
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Extended Deligne-Lusztig varieties for general and special linear groups [PDF]
We give a generalisation of Deligne-Lusztig varieties for general and special linear groups over finite quotients of the ring of integers in a non-archimedean local field.
Stasinski, Alexander
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Co-rank 1 $1$ 1 Arithmetic Siegel–Weil IV: Analytic local-to-global
Forum of Mathematics, SigmaThis is the fourth in a sequence of four papers, where we prove the arithmetic Siegel–Weil formula in co-rank 1 $1$ 1 for Kudla–Rapoport special cycles on exotic smooth integral models of unitary Shimura varieties of arbitrarily large even ...
Ryan Chen
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Sears special and Virginia 310: new varieties of Virginia fire-cured tobacco [PDF]
, 1968 Describes Sears Special and Virginia 310, two new varieties of tobacco released for seed increaseResearch Division ...
Spasoff, L., Henderson, Robert G.
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