Results 171 to 180 of about 18,271 (281)

From Permits to Samples: Addressing Key Challenges for High-Quality Reference Genome Generation in Europe. [PDF]

Mol Ecol Resour
Reichel K, Pohjoismäki J, Astrin JJ, Böhne A, Bortoluzzi C, Bužan E, Del Campo J, Ciofi C, Di-Nizo CB, Divakar PK, Greve C, Hampl V, Hilgers L, Laine VN, Leonard JA, Lozano-Fernandez J, Lukić Bilela L, Mazzoni CJ, McCartney AM, Melo-Ferreira J, Monteiro R, Oomen RA, Pavlek M, Pimenta J, Rindos M, Seehausen O, Tarieiev A, Tomasello S, Vinnere Pettersson O, Waterhouse RM, Weber AA, Zinenko O, de Guttry C.   +32 more
europepmc   +1 more source

Combining Spatial Multi‐Omics Data to Decipher Spatial Domains and Elucidate Cell Heterogeneity Based on Self‐Supervised Graph Learning

Advanced Science, EarlyView.
A self‐supervised multi‐view graph fusion framework integrates spatial multi‐omics, excelling in domain identification and denoising. It reconstructs spatial pseudo‐expression, jointly analyzes multi‐omics data, infers RNA velocity, predicts spatial omics features from single‐cell multi‐omics, and detects spatially dark genes and transcription factors,
Yuejing Lu, Rui Qiao, Ying Li, Junhong Li, Nuoya Yue, Jing Ge, Jiao Wang, Luonan Chen, Peiluan Li   +8 more
wiley   +1 more source

Mapping the current landscape of Klinefelter Syndrome registries: a scoping review. [PDF]

BMJ Open
Stephenson F, Morris A, Arulkkumaran N, Lorenzo A, Mehta S, Cotton A, Yap T.   +6 more
europepmc   +1 more source

Brown Adipocyte Sheets Alleviate Myocardial Ischemia–Reperfusion Injury Through NRG4–ErbB4–Dependent Ferroptosis Inhibition

Advanced Science, EarlyView.
Brown adipocyte sheets are engineered to protect the heart against myocardial ischemia–reperfusion injury by restraining ferroptosis. Upon transplantation onto the cardiac surface, they improve cardiac function, limit infarction and fibrosis, and enhance angiogenesis.
Lifu Sun, Yuting Liu, Jingbo Zhang, Takuji Kawamura, Junjun Li, Li Liu, Shigeru Miyagawa   +6 more
wiley   +1 more source

Generalisation of automatic tumour segmentation in histopathological whole-slide images across multiple cancer types. [PDF]

NPJ Precis Oncol
Skrede OJ, Pradhan M, Isaksen MX, Hveem TS, Vlatkovic L, Nesbakken A, Lindemann K, Kristensen GB, Kasius J, Zeimet AG, Brustugun OT, Busund LR, Richardsen EH, Haug ES, Brennhovd B, Rewcastle E, Lillesand M, Kvikstad V, Janssen E, Kerr DJ, Liestøl K, Albregtsen F, Kleppe A.   +22 more
europepmc   +1 more source

Sulfated Cyclocarya Paliurus Polysaccharide Sorchestrates the Gut Microbiome to Mobilize a Host‐Derived 12‐HEPE Against Ulcerative Colitis

Advanced Science, EarlyView.
A sulfated polysaccharide (SCP) from Cyclocarya paliurus alleviates ulcerative colitis by reshaping the gut microbiome. This remodeled microbiota orchestrates the upregulation of the host‐derived lipid 12‐HEPE, which directly inhibits the TLR4/NF‐κB pathway to suppress inflammation.
Xianxiang Chen, Mingyue Shen, Rui Zhang, Zhibing Huang, Hui Niu, Qiang Yu, Yi Chen, Xiangwen Pan, Liyuan Rong, Huiliang Wen, Jun Yang, Jianhua Xie   +11 more
wiley   +1 more source

Visible yet Invisible: embodied meanings of weight stigma among women with binge eating disorder and higher weight. [PDF]

Int J Qual Stud Health Well-being
Berg KH, Natvik E, Jahren L, Eik-Nes TT.
europepmc   +1 more source

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

Advanced Science, EarlyView.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li, Zhonglian Cao, Rongrui Zhou, Xu Cheng, Xiaozhi Hu, Shuwen Xu, Zihan Dou, Ling Du, Dianwen Ju   +8 more
wiley   +1 more source

Detection of Gene Fusions in Soft Tissue Sarcoma Using Next-Generation Sequencing. [PDF]

Genes (Basel)
Remiszewski P, Bobak K, Piątkowski J, Golik P, Tysarowski A, Seliga K, Spałek MJ, Szumera-Ciećkiewicz A, Wągrodzki M, Rutkowski P, Czarnecka AM.   +10 more
europepmc   +1 more source