Results 151 to 160 of about 1,275,466 (358)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Story Musgrave, mission specialist

open access: yes, 1983
This image reflects Story Musgrave, mission specialist, during head rotation ...

core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

The distributional impact of increased school resources: the Specialist Schools Initiative and the Excellence in Cities Programme

open access: yes
This paper estimates the impact of the Specialist Schools initiative and the Excellence in Cities programme on the attainment of secondary school pupils in England. The focus is on their relative impact across gender and ethnic groups.
G Migali, Jim Taylor, S Bradley
core  

Identifying drivers of demographic rates in an at‐risk population of marine mammals using integrated population models

open access: yesEcosphere
Effective conservation of threatened populations requires identification of the processes limiting recovery. When multiple population processes are potentially limiting, they are sometimes analyzed independently, often using different datasets ...
Benjamin W. Nelson   +4 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Generic education for specialist information professionals

open access: yes, 2001
Debate concerning specialist and generalist education for law librarianship is ...
Middleton, Michael R.   +1 more
core  

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