Advanced Science, EarlyView.By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang +27 more
wiley +1 more source
Specialist nurse-led cross-linking service for Keratoconus, the Leeds experience. [PDF]
Eye (Lond), 2023 Prajapati R +7 more
europepmc +1 more source
The importance of diabetes specialist nurses [PDF]
, 2015 The epidemiology of diabetes and dramatic increase in the number of people with diabetes is well documented in literature and this calls for effective management of this long-term condition.
Lawal, Muili
core
Specialist Ambulance Nurses’ Perceptions of Nursing: A Phenomenographic Study [PDF]
, 2020 Lena Forsell +3 more
openalex +1 more source
Material‐Induced Nuclear Deformation Controls Chromatin Architecture in Adipose Stem Cells
Advanced Science, EarlyView.Tuning cell and cytoskeleton mechanics modulated nuclear shape and heterochromatin organization in ASCs. Distinct cytoskeletal architectures induced nuclear morphologies from oblate to prolate ellipsoids. Large elongated cells with a structured actin cap exhibited high nuclear strain, driving nuclear envelope deformation and heterochromatin ...
Carlo F. Natale +6 more
wiley +1 more source
The role of specialist nurses for organ donation: A solution for maximising organ donation rates?
, 2018 Jennifer Tocher +3 more
openalex +2 more sources
Implementing a working together model for Aboriginal patients with acute coronary syndrome: an Aboriginal Hospital Liaison Officer and a specialist cardiac nurse working together to improve hospital care [PDF]
, 2014 Karen Daws +7 more
openalex +1 more source
Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer
Advanced Science, EarlyView.The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang +10 more
wiley +1 more source
Application of a specialist nurse-led multidisciplinary team model in the perioperative care of patients undergoing simultaneous pancreas and kidney transplantation: randomized controlled trial. [PDF]
Gland Surg, 2023 Zhang W +8 more
europepmc +1 more source
Principles for Rigorous Design and Application of Synthetic Microbial Communities
Advanced Science, EarlyView.SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang +21 more
wiley +1 more source