Results 61 to 70 of about 99,252 (304)

Prescribing and the epilepsy specialist nurse

open access: yes, 2003
Increasingly, the epilepsy nurse specialist has become an integral part of the specialist epilepsy team. Nurse specialists, who practice at an advanced level, frequently advise patients on diagnosis and antiepileptic drug changes.
HOSKING, P
core   +1 more source

A Paradigm Shift in Nurse Specialist Clinical Supervision—Implementation of a Competence Program

open access: yesSAGE Open Nursing, 2019
The change of the anesthesia-, intensive-, surgery-, and oncological nursing postgraduate education into clinical-oriented master programs makes it necessary to increase the professional skills of nurse specialist clinical supervisors.
Anne Lind Jølstad ORN, RNT, MNSc   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Divisional review of the nurse specialist role

open access: yes, 2019
Nurse specialists have been described as providing an optimal return on investment for income generation, patient safety, cost savings, and improvements in patient care and experience.
Purser, Scott   +3 more
core   +1 more source

Immunization Coverage in Young People Experiencing Homelessness and the Impact of a Nurse-led Program

open access: yesJournal of Primary Care & Community Health, 2023
Objectives: To identify the proportion of young people experiencing homelessness who are immunized against vaccine-preventable diseases, and to evaluate the impact of a nurse-led immunization program to improve vaccination coverage in this population ...
Belinda L. Tominc   +5 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Construction of training program for cardiac rehabilitation specialist nurse

open access: yesHuli yanjiu, 2023
ObjectiveTo construct the training program for cardiac rehabilitation specialist nurse,so as to provide reference basis for the training of cardiac rehabilitation specialist nurses in China.MethodsThrough literature review and semi-structured interview ...
LIU Shuo   +3 more
doaj  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

A Study on the Qualifications and Ways of Selecting Candidates of Clinical Nurse Specialist in China

open access: yesHuli yanjiu, 2003
Objective: to understand the viewpoints of nursing staffs towards the essential qualifications and ways of selecting candidates of clinical nurse specialists in our country, and to provide a basis for the establishment of an eligible criteria for ...
王欣, 王惠珍
doaj  

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