Results 41 to 50 of about 697,557 (339)

Exploring Rosiglitazone’s Potential to Treat Alzheimer’s Disease through the Modulation of Brain-Derived Neurotrophic Factor

Biology, 2023
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that debilitates over 55 million individuals worldwide. Currently, treatments manage and alleviate its symptoms; however, there is still a need to find a therapy that prevents or halts ...
Mackayla L. Nelson, Julia A. Pfeifer, Jordan P. Hickey, Andrila E. Collins, Bettina E. Kalisch   +4 more
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Effectivness of specific mobile health applications (mHealth-apps) in gestational diabtetes mellitus: a systematic review

BMC Pregnancy and Childbirth, 2021
Background Gestational diabetes mellitus (GDM) emerges worldwide and is closely associated with short- and long-term health issues in women and their offspring, such as pregnancy and birth complications respectively comorbidities, Type 2 Diabetes (T2D ...
Claudia Eberle, Maxine Loehnert, Stefanie Stichling   +2 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Special moments

Advances in Applied Mathematics, 2005
8 pages, 2 figures. Substantially revised and expanded with the aid of a careful referee.
openaire   +4 more sources

Verdier specialization via weak factorization

, 2012
Let X in V be a closed embedding, with V - X nonsingular. We define a constructible function on X, agreeing with Verdier's specialization of the constant function 1 when X is the zero-locus of a function on V.
A. Parusiński, A. Parusiński, A. Parusiński, C. Sabbah, D. Abramovich, E. Brieskorn, F. Bittner, G. Kennedy, G. Kennedy, J. Denef, J. Denef, J. H. G. Fu, J.-L. Verdier, J.-L. Verdier, J.-P. Brasselet, J.-P. Brasselet, K. Behrend, L. Proeyen Van, M.-H. Schwartz, M.-H. Schwartz, N. A’Campo, P. Aluffi, P. Aluffi, P. Aluffi, P. Aluffi, P. Aluffi, P. Aluffi, P. Aluffi, P. Aluffi, Paolo Aluffi, R. D. MacPherson, W. Fulton   +31 more
core   +1 more source

Migraine diagnosis in patients with sinus headache symptoms: a cross-sectional study at Khartoum ENT Hospital

The Egyptian Journal of Otolaryngology
Background Sinus headache is the most common diagnosis reported by patients with migraine who received a non-migraine diagnosis. Thus, the aim of this study was to determine the prevalence of migraine among patients present with sinus headache to ...
Mohamed Salah Mohamed Abdelgafour, Abdelgadir Ahmed Eltayeb, Mohammed El-Awad   +2 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Technical aspects of reconstruction for inadequate left atrial cuff in lung transplantation

Journal of Cardiothoracic Surgery, 2023
Objective Lung transplantation is the only life-saving treatment for lung diseases that do not respond to medical treatment. Heart-lung harvesting requires a careful procedure to protect an adequate donor left atrial cuff around the junction of the ...
Sevinc Citak, Murat Ersin Cardak
doaj   +1 more source