Results 81 to 90 of about 262,521 (313)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Regional Specialization via Differences in Transport Costs [PDF]

This paper examines a new economic geography model with multiple (three) industries and urban costs. The industries are asymmetric in their transport costs. The following results were obtained.
Hajime Takatsuka, Dao-Zhi Zeng
core  

Clinical Outcomes of Percutaneous Mitral Valve Repair with Mitraclip®: A Longitudinal Observational Study (The Mitra-Angio-CDO Study)

Therapeutics and Clinical Risk Management
Luis Álvaro Melo-Burbano,1– 3 Diana Marcela Bonilla-Bonilla,1– 3 Jorge Enrique Daza-Arana,1,4 Heiler Lozada-Ramos,1,3– 5 Antonio Enrique Dager,6 Jaime Andrés Fonseca6 1School of Health, Internal Medicine Specialization Program, Universidad Santiago de ...
Melo-Burbano LÁ, Bonilla-Bonilla DM, Daza-Arana JE, Lozada-Ramos H, Dager AE, Fonseca JA   +5 more
doaj  

Ileocecal volvulus in an infant with dorsal mesenteric agenesis: A case report

Journal of Pediatric Surgery Case Reports
Introduction: Intestinal volvulus due to agenesis of the dorsal mesentery is an exceptionally rare cause of intestinal obstruction in infants, with few cases reported in the literature.
Alaa Eltayeb, Abdelrahman S. Elnour, Rammah Bireama, Yousif Faisal, Faisal Nugud   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

International Vertical Specialization, Imperfect Competition and Welfare [PDF]

This paper looks at the impact of international vertical specialization when the final good industry is imperfectly competitive. Final goods are assembled out of different fragments.
GOH, Ai ting, OLIVIER, Jacques
core  

05491 Executive Summary – Spatial Cognition: Specialization and Integration [PDF]

, 2007
Spatial Cognition: Specialization and ...
Freksa, Christian
core   +1 more source

Actinomycosis: Mimicking Malignancies in Multiple Anatomical Sites—A Three-Patient Case Series

Medicina
Background and Objectives: Actinomycosis is a rare chronic contagion caused by Actinomyces spp. known for its ability to mimic malignant processes across various anatomical locations.
John Fernando Montenegro, Vanessa Correa Forero, Yamil Liscano, Andres Grueso Pineda, Diana Marcela Bonilla Bonilla, Paola Andrea Ruiz Jimenez   +5 more
doaj   +1 more source

Special Holonomy on Special Spaces

, 2014
We characterise simply-connected biquotients which potentially admit metrics of holonomy G_2. We prove that there are at most three real homotopy types of rationally elliptic such manifolds---all of them being formal. In the course of this examination we classify rationally elliptic homotopy types and characterise 7-dimensional simply-connected ...
openaire   +3 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source