Resistin targets TAZ to promote osteogenic differentiation through PI3K/AKT/mTOR pathway
iScience, 2023 Summary: Osteogenic differentiation (OD) of bone marrow mesenchymal stem cells (BMSCs) contributes significantly to the regeneration of bone defects.
JingJing Shang +7 more
doaj +1 more source
Flagellar membrane association via interaction with lipid rafts [PDF]
, 2009 The eukaryotic flagellar membrane has a distinct composition from other domains of the plasmalemma. Our work shows that the specialized composition of the trypanosome flagellar membrane reflects increased concentrations of sterols and saturated fatty ...
Cieslak, John A. +6 more
core +2 more sources
Culture medium geometry. The dominant factor affecting in vitro RF exposure dosimetry [PDF]
, 2015 Biological experiments that expose living cells or tissues to RF energy must have an aqueous medium to provide essential water, ions, nutrients, and growth factors.
Apollonio, Francesca +5 more
core +3 more sources
The Immunomodulatory Functions of Mesenchymal Stromal/Stem Cells Mediated via Paracrine Activity
Journal of Clinical Medicine, 2019 Mesenchymal stromal/stem cells (MSCs) exist in almost all tissues, possessing the potential to differentiate into specialized cell types and exert immunomodulatory functions.
Yueyuan Zhou +3 more
semanticscholar +1 more source
iScience, 2023 Summary: We performed direct RNA sequencing (DRS) together with PCR-amplified cDNA long and short read sequencing for cattle adipocyte at different stages.
Lingwei Peng +10 more
doaj +1 more source
The Arabidopsis Synaptotagmin1 is enriched in endoplasmic reticulum-plasma membrane contact sites and confers cellular resistance to mechanical stresses [PDF]
, 2015 Eukaryotic endoplasmic reticulum (ER)-plasma membrane (PM) contact sites are evolutionarily conserved microdomains that have important roles in specialized metabolic functions such as ER-PM communication, lipid homeostasis, and Ca2+ influx.
Botella, Miguel A +8 more
core +2 more sources
Profound Re-Organization of Cell Surface Proteome in Equine Retinal Pigment Epithelial Cells in Response to In Vitro Culturing [PDF]
, 2012 The purpose of this study was to characterize the cell surface proteome of native compared to cultured equine retinal pigment epithelium (RPE) cells. The RPE plays an essential role in visual function and represents the outer blood-retinal barrier.
Aisenbrey +54 more
core +3 more sources
Human Dendritic Cell Functional Specialization in Steady-State and Inflammation [PDF]
Frontiers in Immunology, 2014 Dendritic cells (DC) represent a heterogeneous population of antigen-presenting cells that are crucial in initiating and shaping immune responses. Although all DC are capable of antigen-uptake, processing, and presentation to T cells, DC subtypes differ in their origin, location, migration patterns, and specialized immunological roles.
Arjan Boltjes, Femke van Wijk
openaire +3 more sources
Exploring the dynamics and influencing factors of CD4 T cell activation using single-cell RNA-seq
iScience, 2023 Summary: T cell activation is a key event in adaptive immunity. However, the dynamics and influencing factors of T cell activation remain unclear. Here, we analyzed CD4 T cells that were stimulated with anti-CD3/CD28 under several conditions to explore ...
Hui Li +9 more
doaj +1 more source
Functionally specialized junctions between endothelial cells of lymphatic vessels [PDF]
The Journal of Cell Biology, 2007 Recirculation of fluid and cells through lymphatic vessels plays a key role in normal tissue homeostasis, inflammatory diseases, and cancer. Despite recent advances in understanding lymphatic function (Alitalo, K., T. Tammela, and T.V. Petrova. 2005. Nature.
Hiroya Hashizume +16 more
openaire +6 more sources