Results 51 to 60 of about 7,826,924 (279)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Regional Strategic Analysis and Knowledge Support System (ReSAKSS)

, 2020
Regional strategic analysis and knowledge support system (ReSAKSS) is a Africa-focused database nodes that compile, analyze, and disseminate data, information, and tools to help design, implement, monitor, and evaluate rural development strategies.Non ...
Regional Strategic Analysis and Knowledge Support System (ReSAKSS)
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Legal Status and Assessment of the Competence of a Forensic Expert and Specialist: Conceptual Framework and Practical Implementation

Теория и практика судебной экспертизы
Currently, in connection with the social and scientific and practical metamorphoses, special attention is paid to the problems of differentiation of forensic expert’s and specialist’s specialized knowledge, as well as the results of their activities ...
M. V. Zhizhina, G. G. Omel’yanyuk, I. A. Lapina   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

USING SPECIALIZED KNOWLEDGE IN THE INVESTIGATION OF CRIMES UNDER ARTICLES 242, 242.1, 242.2 OF THE CRIMINAL CODE OF THE RUSSIAN FEDERATION

Правовое государство: теория и практика
Liability for the illicit production and trafficking of pornographic materials or objects, production and trafficking of materials or objects with pornographic images of minors, and the use of a minor for the production of pornographic materials or ...
IVANOVA Elena Vyacheslavovna, DYAKONOVA Oksana Gennadievna   +1 more
doaj   +1 more source

Knowledge Modeling and Incident Analysis for Special Cargo

, 2021
AbstractThe airfreight industry of shipping goods with special handling needs, also known as special cargo, suffers from nontransparent shipping processes, resulting in inefficiency. The LARA project (Lane Analysis and Route Advisor) aims at addressing these limitations and bringing innovation in special cargo route planning so as to improve ...
V. Reshadat (Vahideh), T. Kolkman (Tess), K. Zervanou (Kalliopi), Zhang, Y. (Yingqian), A. Akçay (Alp), C. Snijder (Carlijn), R. McDonnell (Ryan), K. Schorer (Karel), C. Wichers (Casper), T. H. A. Koch (Thomas), E.R. Dugundji (Elenna), E. de Jong (Eelco)   +11 more
openaire   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source