Stress-mediated cis-element transcription factor interactions interconnecting primary and specialized metabolism in planta [PDF]
Frontiers in Plant Science, 2016 Plant specialized metabolites are being used worldwide as therapeutic agents against several diseases. Since the precursors for specialized metabolites come through primary metabolism, extensive investigations have been carried out to understand the ...
S. A. Sheshadri +2 more
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Chromosomal organization of biosynthetic gene clusters, including those of nine novel species, suggests plasticity of myxobacterial specialized metabolism [PDF]
Frontiers in Microbiology, 2023 IntroductionNatural products discovered from bacteria provide critically needed therapeutic leads for drug discovery, and myxobacteria are an established source for metabolites with unique chemical scaffolds and biological activities.
Andrew Ahearne +5 more
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Stress-Induced Plant Specialized Metabolism: Signaling, Multi-Omics Integration, and Plant-Derived Antimicrobial Metabolites to Combat Antimicrobial Resistance [PDF]
PlantsAntimicrobial resistance (AMR) is one of the major health threats of the 21st century and demands innovative sources of bioactive compounds. In 2019, infections caused by resistant bacteria directly accounted for 1.27 million deaths and contributed to an
Luis Enrique Pérez-Sánchez +4 more
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Mining the Biosynthetic Potential for Specialized Metabolism of a Streptomyces Soil Community [PDF]
Antibiotics, 2020 The diversity and distribution of specialized metabolite gene clusters within a community of bacteria living in the same soil habitat are poorly documented.
Matthieu Nicault +6 more
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Cooperation, Competition, and Specialized Metabolism in a Simplified Root Nodule Microbiome [PDF]
mBio, 2020 Microbiomes associated with various plant structures often contain members with the potential to make specialized metabolites, e.g., molecules with antibacterial, antifungal, or siderophore activities.
Bridget L. Hansen +6 more
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Non-Infectious Dermatological Manifestations among Patients with Diabetes Mellitus in Basrah, Iraq [PDF]
Archives of Razi Institute, 2022 Diabetes mellitus (DM) is a clinical illness usually linked to a wide range of skin manifestations; however, skin, as the greatest organ in the body, has received little attention. As a result, this study aimed to detect the prevalence and pattern of non-
A Sabah Abdulridha Budair +2 more
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Total Testosterone to Estradiol Ratio as a Predictor Marker of Metabolic Syndrome in Males [PDF]
Archives of Razi Institute, 2022 Nowadays, metabolic syndrome (MetS) represents a global health challenge in developed and developing countries. The sex hormones disorders in males are related to many clinical co-morbidities.
Ali Muqdamal +2 more
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Hairy Roots of Scutellaria spp. (Lamiaceae) as Promising Producers of Antiviral Flavones
Molecules, 2021 We measured and studied the growth parameters and the qualitative and quantitative composition of the flavones of hairy roots of the Scutellaria genus: S. lateriflora, S. przewalskii and S. pycnoclada.
Anna Yurievna Stepanova +5 more
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A Study of Combined Oral Anti-Diabetic Drugs during Ramadan
Clinical Diabetology, 2022 BACKGROUND: The safety and efficacy of combination tablets of metformin plus sulfonylurea or plus dipeptidyl peptidase-4 inhibitors have not been studied previously.
Majid H Alabbood +5 more
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Indonesian Biomedical Journal, 2021 BACKGROUND: Obese women with polycystic ovary syndrome (PCOS) are at high risk for developing type 2 diabetes mellitus (T2DM). A baseline oral glucose tolerance test (2-h OGTT) is important to screen for dysglycemia in PCOS particularly those high risk ...
Mahmood Thamer Altemimi +2 more
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