Results 101 to 110 of about 325,721 (301)
Plants produce a vast array of structurally diverse specialized metabolites with various biological activities, including medicinal alkaloids and terpenoids, from relatively simple precursors through a series of enzymatic steps.
Tsubasa Shoji
doaj +1 more source
Thaxtomin A is a potent phytotoxin that serves as the principle pathogenicity determinant of the common scab pathogen, Streptomyces scabiei, and is also a promising natural herbicide for agricultural applications. The biosynthesis of thaxtomin A involves
Yuting Li +2 more
doaj +1 more source
Antoni Kępiński’s Philosophy of Medicine – an alternative reading [PDF]
Antoni Kępiński remains an often read and quoted author even 40 years after his premature death. Usually he is read in the context of his times and his connections with contemporary philosophy.
Zawiła-Niedźwiecki, Jakub
core +2 more sources
Myocardial Amide-nitrogen Metabolism with Special Reference to Ammonia Metabolism
In order to elucidate the significance of ammonia in the myocardium, the dynamic changes of the related substances were studied mainly in the rabbit myocardium. In the experimentally hypertrophied heart, ammonia and urea were slightly in-creased, while ATP, high energy phosphate and total nucleotide were decreased.
openaire +3 more sources
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen +5 more
wiley +1 more source
A Metabolic Complex Involved in Tomato Specialized Metabolism
AbstractSpecialized metabolites mediate diverse plant-environment interactions. Although, recent work has begun to enzymatically characterize entire plant specialized metabolic pathways, little is known about how different pathway components organize and interact within the cell.
Dwivedi, Varun +3 more
openaire +2 more sources
Frailty Exacerbates Disability in Progressive Multiple Sclerosis
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks +10 more
wiley +1 more source
Establishing conserved biosynthetic gene clusters of the phylum Myxococcota
A surge in sequenced myxobacteria catalyzed by advancements in long-read genome and metagenome sequencing has provided sufficient data to scrutinize the conserved biosynthetic gene clusters (BGCs) within the phylum Myxococcota.
Shailaja Khanal Pokharel +6 more
doaj +1 more source
A Unifying Scenario on the Origin and Evolution of Cellular and Viral Domains [PDF]
The cellular theory on the nature of life has been one of the first major advancements in biology. Viruses, however, are the most abundant life forms, and their exclusion from mainstream biology and the Tree of Life (TOL) is a major paradox in biology ...
Claudiu I. Bandea
core +1 more source

