Results 31 to 40 of about 65,753 (249)

Accuracy of interproximal enamel reduction during clear aligner treatment

Progress in Orthodontics, 2020
Aim The aim of the present study was to compare the accuracy of the actual space obtained through interproximal enamel reduction (IPR) compared to the amount of IPR planned through the digital setup during clear aligner treatment (CAT).
Maria Elena De Felice, Ludovica Nucci, Adriana Fiori, Carlos Flores-Mir, Letizia Perillo, Vincenzo Grassia   +5 more
doaj   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Standerd cervical mediastinoscopy in the diagnosis of mediastinal mass in Ghazi Al-Hariri Hospital

مجلة كلية الطب, 2016
Background: Mediastinoscopy is an integral part in the diagnosis of mediastinal mass. The most common indications for mediastinoscopy is for tissue sampling and determining the extent of lung cancer.
Sabah N. Jaber, Abdulameer M. Hussein, Bashar B Aday   +2 more
doaj   +1 more source

Craniomandibular Disorders in Pregnant Women: An Epidemiological Survey

Journal of Functional Morphology and Kinesiology, 2020
Temporomandibular joint (TMJ) disorder has been reported to be 1.5 to two times more common in women than men. Such a gender-based difference could be attributed to behavioral, hormonal, anatomical, and psychological characteristics.
Grazia Fichera, Alessandro Polizzi, Simone Scapellato, Giuseppe Palazzo, Francesco Indelicato   +4 more
doaj   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Indications for Dental Specialists for Treating Obstructive Sleep Apnea with Mandibular Advancement Devices: A Narrative Review

International Journal of Dentistry
Obstructive sleep apnea (OSA) syndrome is characterized by repeated airway collapse during sleep. It determines cardiovascular, pulmonary, and neurocognitive consequences and is associated with several daytime and nighttime symptoms that influence the ...
Antonino Lo Giudice, Salvatore La Rosa, Vincenzo Ronsivalle, Gaetano Isola, Marco Cicciù, Giulio Alessandri-Bonetti, Rosalia Leonardi   +6 more
doaj   +1 more source

Complex Regional Pain Syndrome in Athletes: Scoping Review

Medicina, 2021
Background and Objectives: Complex regional pain syndrome (CRPS) is a chronic condition characterized by disproportionate regional pain, usually affecting distal limbs, that follows trauma or surgery.
Antimo Moretti, Angela Palomba, Marco Paoletta, Sara Liguori, Giuseppe Toro, Giovanni Iolascon   +5 more
doaj   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Groove pancreatitis treated by duodenal and biliary bypass

Journal of Pediatric Surgery Case Reports, 2020
Background: Groove pancreatitis is a type of pancreatitis where inflammation occurs in the “groove area” which is the narrow space surrounded by the duodenum, head of the pancreas and common bile duct, where lymph nodes, blood vessels and pancreatic duct
Kazunori Tahara, Yutaka Kanamori, Kazue Miyake, Yumi Kudo, Takuro Fujita, Mai Kutsukake, Teizaburo Mori, Yohei Yamada, Akihiro Fujino, Hirotaka Shimizu, Katsuhiro Arai, Yoshiyuki Tsutsumi, Osamu Miyazaki   +12 more
doaj