Results 131 to 140 of about 763,696 (279)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

Electronic Consultations Between Primary and Specialty Care Clinicians: Early Insights [PDF]

open access: yes, 2011
Outlines how e-consultation enables clinicians and specialists to communicate more easily and reduce the need for in-person referrals; experiences for patients, clinicians, and health systems; benefits such as continuity of care; and barriers to ...
Ed Wagner, Jim Tufano, Kathryn Horner
core  

Stretching the Printability Metric in Direct‐Ink Writing with Highly Extensible Yield‐Stress Fluids

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces “drawability” as a new metric for assessing printability in direct‐ink writing, focusing on gap‐spanning performance and speed robustness. By designing yield‐stress fluids with high extensibility, we demonstrate that extensional strain‐to‐break significantly enhances printability.
Chaimongkol Saengow   +9 more
wiley   +1 more source

Electroactive Metal–Organic Frameworks for Electrocatalysis

open access: yesAdvanced Functional Materials, EarlyView.
Electrocatalysis is crucial in sustainable energy conversion as it enables efficient chemical transformations. The review discusses how metal–organic frameworks can revolutionize this field by offering tailorable structures and active site tunability, enabling efficient and selective electrocatalytic processes.
Irena Senkovska   +7 more
wiley   +1 more source

End‑of‑life care in advanced melanoma: a retrospective cohort study from an Italian comprehensive cancer center

open access: yesBMC Cancer
Background Despite improvements in overall survival (OS) with immune-checkpoint inhibitors (ICIs) and targeted therapies, many patients with advanced melanoma and non-melanoma skin cancer still experience disease progression (PD) and remain on systemic ...
Michela De Mattia   +11 more
doaj   +1 more source

New System of Japanese Medical Specialty : Internal Medicine

open access: yesOkayama Igakkai Zasshi (Journal of Okayama Medical Association), 2018
Mikako Obika   +2 more
openaire   +2 more sources

Comparison of Different Temperatures on Bending Properties of Six Niti Endodontic File Systems [PDF]

open access: yes, 2018
Introduction: Manufacturers claim that modern NiTi files with proprietary heat treatment transform at higher temperatures, thus staying more martensite and being more resistant to cyclic fatigue and more flexible.
Yoo, Sukbum
core   +1 more source

3D‐Printed Sulfur‐Derived Polymers With Controlled Architectures for Lithium‐Sulfur Batteries

open access: yesAdvanced Functional Materials, EarlyView.
Rheology‐guided formulation design for direct ink writing enables the fabrication of 3D sulfur copolymer cathodes with controlled architectures for lithium‐sulfur batteries. The printed electrodes exhibit multiscale porosity and high sulfur utilization, delivering enhanced electrochemical performance compared to conventional cast electrodes.
Bin Ling   +7 more
wiley   +1 more source

Career goals of trainee physicians in internal medicine [PDF]

open access: yes, 2008
OBJECTIVE: To survey Internal Medicine trainees\u27 future career choices and factors influencing their decision-making. DESIGN: Cross-sectional study. PLACE AND DURATION OF STUDY: The Aga Khan University Hospital, Karachi, from November 2006 to January ...
Akhtar, Jaweed   +9 more
core   +1 more source

Bio‐Inspired Molecular Events in Poly(Ionic Liquids)

open access: yesAdvanced Functional Materials, EarlyView.
Originating from dipolar and polar inter‐ and intra‐chain interactions of the building blocks, the topologies and morphologies of poly(ionic liquids) (PIL) govern their nano‐ and micro‐processibility. Modulating the interactions of cation‐anion pairs with aliphatic dipolar components enables the tunability of properties, facilitated by “bottom‐up ...
Jiahui Liu, Marek W. Urban
wiley   +1 more source

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