Results 31 to 40 of about 763,696 (279)

The specialty choices of graduates from Brighton and Sussex Medical School: a longitudinal cohort study [PDF]

, 2015
BACKGROUND Since 2007 junior doctors in the UK have had to make major career decisions at a point when previously many had not yet chosen a specialty.
B Fischhoff, C Edwards, C Elton, Caroline Elton, CZ Mooney, D Campos-Outcalt, G Maudsley, IC McManus, IC McManus, IC McManus, J Cleland, J Tooke, K Woolf, Katherine Woolf, M Albert, Melanie Newport, MJ Goldacre, MJ Goldacre, MJ Goldacre, ML Goldacre, P Ravindra, PT Costa, R Mahoney, R Schwarzer, RJ Markert, S Fazel, SE Straus, V Luther   +27 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Efficacy of a coordinated strategy for containment of multidrug-resistant Gram-negative bacteria carriage in a Neonatal Intensive Care Unit in the context of an active surveillance program

Antimicrobial Resistance and Infection Control, 2021
Background Antimicrobial resistance in neonatal intensive care unit (NICU) patients is a threat, due to the frequent use of antimicrobial treatment and invasive devices in fragile babies.
Laura Saporito, Giorgio Graziano, Federica Mescolo, Emanuele Amodio, Vincenzo Insinga, Grazia Rinaudo, Aurora Aleo, Celestino Bonura, Marcello Vitaliti, Giovanni Corsello, Francesco Vitale, Carmelo Massimo Maida, Mario Giuffrè   +12 more
doaj   +1 more source

A Snapshot of U.S. Physicians: Key Findings From the 2008 Health Tracking Physician Survey [PDF]

, 2009
Analyzes survey data on U.S. physicians' compensation system, career satisfaction, acceptance of new patients, managed care contracts, and charity care provision by demographics, type of practice, specialty, geographic location, and other ...
Alwyn Cassil, Ann S. O'Malley, Ellyn Boukus   +2 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Poor glycemic control impacts heart rate variability in patients with type 2 diabetes mellitus: a cross sectional study

BMC Research Notes, 2018
Objective We aimed to determine and compare HRV parameters in poorly and well controlled type 2 diabetes. 54 normotensive type 2 diabetes patients without clinical signs of CAN were enrolled; 29 poorly controlled (HbA1c ≥ 7%) and 25 controls matched for ...
Chris Nadège Nganou-Gnindjio, Camille Maadjhou Mba, Marcel Azabji-Kenfack, Mesmin Y. Dehayem, Liliane Mfeukeu-Kuate, Jean-Claude Mbanya, Eugène Sobngwi   +6 more
doaj   +1 more source

Efficacy of Topical Finasteride 0.5% vs 17α-Estradiol 0.05% in the Treatment of Postmenopausal Female Pattern Hair Loss: A Retrospective, Single-Blind Study of 119 Patients

Dermatology Practical & Conceptual, 2020
Background and Objectives: Female pattern hair loss (FPHL) is a common form of scalp hair loss that occurs in 38% of females. Currently, minoxidil solution is the only therapy approved by the US Food and Drug Administration, but many other treatments are
Alfredo Rossi, Francesca Magri, Andrea D'Arino, Flavia Pigliacelli, Marta Muscianese, Pierpaolo Leoncini, Gemma Caro, Alessandro Federico, Maria Caterina Fortuna, Marta Carlesimo   +9 more
doaj   +1 more source

Intestinal malrotation in a female newborn affected by Osteopathia Striata with Cranial Sclerosis due to a de novo heterozygous nonsense mutation of the AMER1 gene

Italian Journal of Pediatrics, 2022
Background Osteopathia Striata with Cranial Sclerosis (OS-CS), also known as Horan-Beighton Syndrome, is a rare genetic disease; about 90 cases have been reported to date.
Gregorio Serra, Vincenzo Antona, Maria Rita Di Pace, Mario Giuffrè, Giusy Morgante, Ettore Piro, Roberto Pirrello, Sergio Salerno, Ingrid Anne Mandy Schierz, Vincenzo Verde, Giovanni Corsello   +10 more
doaj   +1 more source

California Physician Facts and Figures [PDF]

, 2010
Examines trends in the state's supply of primary care physicians, including demographics, specialties, and education and training; acceptance of new patients by coverage type; family and general practitioner compensation; and medical group ...
Craig Paxton
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source