Results 151 to 160 of about 8,964,438 (367)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

When can few-species models describe dynamics within a complex community? [PDF]

open access: yesarXiv
Dynamics of species' abundances in ecological communities are often described using models that only account for a few species. It is not clear when and why this would be possible, as most species form part of diverse ecological communities, with many species that are not included in these few-variable descriptions.
arxiv  

Species of Spaces

open access: yes, 2012
Classical limits of quantum systems are shown to lead to different conceptions of spaces different from the classical one underlying the process of quantization of such systems. The accent is put in situations where traces of noncommutativity, witness of an emblematic feature of quantum mechanise remains when the Planck constant vanishes, in the ...
openaire   +2 more sources

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

A new genus and two new species of African Fruit-flies

open access: green, 1910
Usha Hettiaratchi   +4 more
openalex   +2 more sources

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

open access: yesFEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli   +15 more
wiley   +1 more source

Drietakkig rooddonswier - Antithamnionella ternifolia. Niet-inheemse soorten van het Belgisch deel van de Noordzee en aanpalende estuaria [PDF]

open access: yes, 2011
Het oorsprongsgebied van het drietakkig rooddonswier Antithamnionella ternifolia is eerder onduidelijk, hoewel er vermoedens zijn dat dit roodwier afkomstig is uit de zuidelijke hemisfeer. Dit niet-inheemse roodwier zou in Europese wateren terechtgekomen
VLIZ Alien Species Consortium
core  

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

open access: yesFEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu   +6 more
wiley   +1 more source

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