Results 151 to 160 of about 8,964,438 (367)
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
When can few-species models describe dynamics within a complex community? [PDF]
Dynamics of species' abundances in ecological communities are often described using models that only account for a few species. It is not clear when and why this would be possible, as most species form part of diverse ecological communities, with many species that are not included in these few-variable descriptions.
arxiv
Classical limits of quantum systems are shown to lead to different conceptions of spaces different from the classical one underlying the process of quantization of such systems. The accent is put in situations where traces of noncommutativity, witness of an emblematic feature of quantum mechanise remains when the Planck constant vanishes, in the ...
openaire +2 more sources
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang+9 more
wiley +1 more source
A new genus and two new species of African Fruit-flies
Usha Hettiaratchi+4 more
openalex +2 more sources
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli+15 more
wiley +1 more source
Drietakkig rooddonswier - Antithamnionella ternifolia. Niet-inheemse soorten van het Belgisch deel van de Noordzee en aanpalende estuaria [PDF]
Het oorsprongsgebied van het drietakkig rooddonswier Antithamnionella ternifolia is eerder onduidelijk, hoewel er vermoedens zijn dat dit roodwier afkomstig is uit de zuidelijke hemisfeer. Dit niet-inheemse roodwier zou in Europese wateren terechtgekomen
VLIZ Alien Species Consortium
core
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei+7 more
wiley +1 more source
Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu+6 more
wiley +1 more source