CSF Mitochondrial DNA: Biomarker of Body Composition and Energy Metabolism in Parkinson's Disease
ABSTRACT Objective Cerebrospinal fluid (CSF) cell‐free mitochondrial DNA (cf‐mtDNA) is a potential biomarker for Parkinson's disease (PD), but its clinical relevance remains unclear. We investigated associations between CSF cf‐mtDNA levels, body composition, nutritional status, and metabolic biomarkers in PD. Methods CSF cf‐mtDNA levels, defined as the
Yasuaki Mizutani +11 more
wiley +1 more source
Genetic clustering within massive Porites species complex is the primary driver of holobiont assembly. [PDF]
Scott CB, Schott R, Matz MV.
europepmc +1 more source
ABSTRACT Background Plasma p‐tau181 has proven to be a promising diagnostic and prognostic tool in the earliest phases of Alzheimer's disease (AD). We aimed to evaluate the prognostic role of p‐tau181 in predicting conversion to AD dementia and worsening in cognition in mild cognitive impairment (MCI) and subjective cognitive decline (SCD).
Giulia Giacomucci +12 more
wiley +1 more source
Divergence and Selection in a Cryptic Species Complex (Geonoma undata: Arecaceae) in the Northern Andes of Colombia. [PDF]
Webster CP +5 more
europepmc +1 more source
Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam +6 more
wiley +1 more source
Expansion of the Candidozyma haemuli Species Complex - The Novel Species Candidozyma molenica, Isolated from Clinical and Environmental Sources. [PDF]
Zandijk A +7 more
europepmc +1 more source
RECOGNITION OF TAXONOMICALLY SIGNIFICANT CLUSTERS NEAR THE SPECIES LEVEL, USING COMPUTATIONALLY INTENSE METHODS, WITH EXAMPLES FROM THE STEPHANODISCUS NIAGARAE COMPLEX (BACILLARIOPHYCEAE)1 [PDF]
Matthew L. Julius +3 more
openalex +1 more source

