Results 131 to 140 of about 10,486,597 (353)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Plant compartment and biogeography affect microbiome composition in cultivated and native Agave species

New Phytologist, 2015
Summary Desert plants are hypothesized to survive the environmental stress inherent to these regions in part thanks to symbioses with microorganisms, and yet these microbial species, the communities they form, and the forces that influence them are ...
Devin Coleman-Derr, D. Desgarennes, Citlali Fonseca-García, Stephen Gross, S. Clingenpeel, T. Woyke, G. North, A. Visel, L. Partida-Martínez, S. Tringe   +9 more
semanticscholar   +1 more source

Influence of River Valleys on Genetic Diversity and Species Distribution Patterns of Cyprididae (Crustacea: Ostracoda) on the Tibetan Plateau

Ecology and Evolution
River valleys are recognized as significant ecological barriers that impact gene flow between species adapted to distinct habitat types. The Tibetan Plateau, with its diverse habitats intersected by numerous river valleys, serves as a focal point for ...
Qing Hu, Bingkuan Zhu, Zhihang Ma, Yini Yang, Zhixiong Deng, Shaoqing Wen, Xiaolin Ma   +6 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Volatile Composition ofTrifoliumandMedicagoSpecies

Journal of Essential Oil Bearing Plants, 2011
Abstract The volatile compounds of Trifolium (Leguminosae) echinatum L., Trifolium stellatum var. stellatum L., Trifolium nigrescens subs. petrisavi (Celm) Holmboe, Medicago polymorpha var. vulgaris L., Medicago arabica (L.) Huds. and Medicago minima var. minima (L.) Grufbg.
Sabudak, Temine, Goren, Ahmet C.
openaire   +4 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

How Changes in Plant Community Structure Affect Terrestrial Invertebrate Food Webs [PDF]

, 2016
We investigated how change in plant community composition and vegetative structure brought about by annual grass-specific herbicide application affects terrestrial arthropod communities, with special emphasis on the potential mutualists and predators of ...
LaFountain, Renee, Rasmussen-Rehkopf, Sarah, Schultz, Cheryl, Thurman, Kiera, Tillberg, Chadwick V.   +4 more
core   +1 more source

Diversity of ciliates in small rivers in vicinity of Khabarovsk and in southern Sakhalin Island

Известия ТИНРО, 2016
Data on species composition of ciliates in the small rivers at Khabarovsk and in southern Sakhalin Island are presented. Modified method of sampling was applied with using of samplers and “glass fouling” on the shallows of the rivers.
Alexander G. Panov, Mikhail M. Tribun, Lyudmila I. Nikitina   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Tropical rainforest bird community structure in relation to altitude, tree species composition, and null models in the Western Ghats, India

, 2005
Studies of species distributions on elevational gradients are essential to understand principles of community organisation as well as to conserve species in montane regions.
Joshi, N. V., Raman, T. R. Shankar, Sukumar, R.   +2 more
core