Results 111 to 120 of about 10,486,597 (353)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Mapping the species richness and composition of tropical forests from remotely sensed data with neural networks [PDF]

open access: yes, 2006
The understanding and management of biodiversity is often limited by a lack of data. Remote sensing has considerable potential as a source of data on biodiversity at spatial and temporal scales appropriate for biodiversity management.
Cannon   +22 more
core   +2 more sources

PLANKTON COMMUNITIES IN TWO FJORDS OF WEST SPITSBERGEN

open access: yesTransactions of the Karelian Research Centre of the Russian Academy of Sciences, 2017
Samples of phyto-, bacterio- and zooplankton were collected from two small fjords of West Spitsbergen Island during the spring and summer seasons of 2007–2010.
Larisa Kapustina   +2 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Litter species composition

open access: yes, 2019
Data from Franzese et al. 2019 in the Journal of Vegetation Science: "Land cover change due to non-native pine introduction modifies litter traits of temperate forests in Patagonia".
openaire   +1 more source

Changes in the silver fir forest vegetation 50 years after cessation of active management [PDF]

open access: yes, 2015
Knowledge of the vegetation and the monitoring of its changes in preserved areas is an essential part of effective conservation policy and management.
Kopeć, Dominik, Woziwoda, Beata
core   +4 more sources

Coral Resilience at Malauka`a Fringing Reef, Kāneʻohe Bay, Oʻahu after 18 years

open access: yesJournal of Marine Science and Engineering, 2019
Globally, coral reefs are under threat from climate change and increasingly frequent bleaching events. However, corals in Kāneʻohe Bay, Hawaiʻi have demonstrated the ability to acclimatize and resist increasing temperatures.
Kelsey A. Barnhill, Keisha D. Bahr
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Distribution and sighting frequency of reef fishes in the Florida Keys National Marine Sanctuary [PDF]

open access: yes, 2001
This study analyzed species richness, distribution, and sighting frequency of selected reef fishes to describe species assemblage composition, abundance, and spatial distribution patterns among sites and regions (Upper Keys, Middle Keys, Lower Keys, and ...
Gittings, S.   +3 more
core  

Complementarity and diversity in a soluble model ecosystem

open access: yes, 2002
Complementarity among species with different traits is one of the basic processes affecting biodiversity, defined as the number of species in the ecosystem. We present here a soluble model ecosystem in which the species are characterized by binary traits
D. Lancet   +8 more
core   +1 more source

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