Results 61 to 70 of about 6,565,768 (301)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Review of Campsicnemus species from the Atlantic Ocean Islands (Diptera: Dolichopodidae) [PDF]

open access: yes, 2012
New species Campsicnemus flavissimus sp. nov., C. meridionalis sp. nov., and C. sanctaehelenae sp. nov. are described from St. Helena. A review and key to seven Campsicnemus species inhabiting Azores, Canary Is., Madeira and St. Helena are provided.
Igor Grichanov   +2 more
core   +1 more source

A New Species of Enicospilus Stephens, 1835 (Ichneumonidae, Ophioninae), from Southern Mexico, Parasitic on Zanola verago Cramer, 1777 (Lepidoptera, Apatelodidae), Feeding on Piper neesianum C. DC. (Piperaceae)

open access: yesDiversity
Plant–herbivore–parasitoid systems are poorly studied in the tropics. Enicospilus carmenae Campos and Palacio sp. nov. are described, originating from southern Mexico in the Yucatan Peninsula and establishing a new tri-trophic interaction.
Diego Fernando Campos-Moreno   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Characterization of Iberian species of the genus Pungentus Thorne & Swanger, 1936 (Nematoda, Dorylaimida, Nordiidae) [PDF]

open access: yes, 2013
Several populations of four known species of the genus Pungentus (P. clavatus, P. engadinensis, P. marietani and P. silvestris), collected in the wild and in cultivated soils from the Iberian Peninsula, are studied.
Ciobanu, Marcel   +6 more
core   +1 more source

DESCRIPTION OF A NEW SPECIES OF COPÆODES [PDF]

open access: yesThe Canadian Entomologist, 1882
Copæodes Wrighth.Male.—Expands .9 inch.Upper side yellow-ochre color; costal margin of primaries black on the edge, and hind margins of both wings edged black, scarcely more than a line; costal margin of secondaries broadly bordered black; the ends of the nervules on primaries edged black for a little distance; on the disk a black sexual narrow bar ...
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Use of the Genealogical Sorting Index (GSI) to delineate species boundaries in the Neofusicoccum parvum-Neofusicoccum ribis species complex [PDF]

open access: yes, 2011
Neofusicoccum is a recently described genus of common endophytes and pathogens of woody hosts, previously placed in the genus Botryosphaeria. Many morphological characteristics routinely used to describe species overlap in Neofusicoccum, and prior to the
Hardy, G.E.St.J.   +2 more
core  

DESCRIPTION OF A NEW SPECIES OF OLIVA [PDF]

open access: yesJournal of Molluscan Studies, 1906
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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