Results 81 to 90 of about 6,565,768 (301)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

DESCRIPTION OF A NEW SPECIES OF PAMPHILA [PDF]

open access: yesThe Canadian Entomologist, 1879
P. Dion.Male—Expands 1.2 inch.Upper side has the disk, cell and basel areas pale fulvous, the latter much obscured ; costal margin also fulvous, but obscured, and inclining to red in the sub-costal interspaces; the apex and hind margin broadly bordered with fuscous; stigma long, narrow, formed by two velvety-black spots, the lower one a little back of ...
openaire   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

DESCRIPTION OF A NEW SPECIES OF LATIRUS [PDF]

open access: yesJournal of Molluscan Studies, 1907
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Welcome to InvasiveSpecies.gov!

open access: yes, 2011
This website contains information about the purpose and work of the National Invasive Species Council, including its plans to prevent and manage invasive species, educational materials, budgetary and organizational documents of the Council, and other ...
National Invasive Species Council (U.S.)
core  

Biffarius pacificus, a new species of the Callianassidae (Crustacea: Decapoda: Thalassinidea) from northern Chile [PDF]

open access: yes, 2003
Nine specimens of Biffarius pacificus sp. nov. were collected with a "van Veen" grab at two sublittoral stations off the northern coast of Chile (Iquique, 22º12'S; Patache, 22º45'S) at depths ranging from 17 to 30 m. This is the first record of the genus
Thatje, S., Guzman, G.L., Guzman, G.
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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