Results 101 to 110 of about 6,565,768 (301)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

MALDI-TOF Mass Spectrometry Discriminates Known Species and Marine Environmental Isolates of Pseudoalteromonas [PDF]

open access: yes, 2016
The genus Pseudoalteromonas constitutes an ecologically significant group of marine Gammaproteobacteria with potential biotechnological value as producers of bioactive compounds and of enzymes.
Andrew Nelson   +30 more
core   +1 more source

DESCRIPTION OF A NEW SPECIES OF DORYCEPHALUS [PDF]

open access: yesThe Canadian Entomologist, 1894
♂—Head produced and very flat, rounded in front, wings reaching tip of abdomen; colour gray-brorvn. Length, 9 mm. Length of head, 2.3 mm.Head thin foliaceous, margins very thiu, a median, thicker space, which beneath widens to base of head, forming a convex keel. Eyes touching prothorax.
openaire   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A-Species [PDF]

open access: yes, 2023
We introduce a generalized notion of combinatorial species called $A$-species, where $A$ is a Hopf algebra. The role played by the symmetric group, $S_n$, in the classical theory of species is now replaced with the wreath product $A\wr S_n$. We show that
Hausmann, Erin
core  

Description of new species of Noctuidae

open access: yesNovitates Zoologicae., 1929
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Wileman, A. E., West, R. J.
openaire   +4 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Oregon invasive species action plan

open access: yes, 2005
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF title page (viewed on Aug.

core  

Diversification of prey capture techniques among the piscivores in Lake Tana's (Ethiopia) Labeobarbus species flock (Cyprinidae) [PDF]

open access: yes, 2010
Lake Tana harbours the only known intact species flock of large cyprinid fishes (15 Labeobarbus spp.). One of the most curious aspects of this species flock is the large number (8) of piscivorous species.
Weerd, G.H., van de   +3 more
core   +1 more source

Passalidae (Coleoptera, Scarabaeoidea) from the Caribbean coast of Colombia: synopsis, key, and new species description. [PDF]

open access: yesZookeys, 2023
Jiménez-Ferbans L   +4 more
europepmc   +1 more source

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