Results 91 to 100 of about 1,799,458 (303)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Holotype of Agathymus escalantei Stallings, Turner, and Stallings, 1966 (Lepidoptera: Hesperiidae: Megathyminae) [PDF]
, 2009 Agathymus escalantei Stallings, Turner, and Stallings, 1966 (Lepidoptera: Hesperiidae) is the only described species of Megathyminae known from a single collected individual.
Boyd, Bret M.
core
Eriophyoid mites (Acari: Prostigmata: Eriophyoidea) from the Maltese Islands (Central Mediterranean): new reports and a preliminary check-list [PDF]
, 2008 In the 20th Century, about 20 species of eriophyoids were listed for the Maltese Islands but these reports were entirely based on plant gall surveys.
Lillo, Enrico de +2 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Neotropical IchthyologyMyxiops aphos, new genus and species, is described from a river in the eastern portion of Bahia State, Brazil. Myxiops is distinguished from all other characid genera by the combination of the following features: infraorbitals fused in a unique fashion ...
Angela M. Zanata, Alberto Akama
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
On a new species of intertidal water strider from Brazil (Hemiptera, Gerromorpha, Mesoveliidae)
, 1984 This paper deals with the description of a new species of Hemiptera, Gerromorpha, Mesoveliidae, from Marudá, State of Pará, Brazil - Darwinivelia polhemi n. sp.
Carvalho, J.
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Re-description of Dysponetus joeli Olivier et al., 2012 (Polychaeta, Chrysopetalidae), with a new key to species of the genus [PDF]
, 2012 Dysponetus is a genus of the family Chrysopetalidae with twelve currently described species. Specimens are fragile and easily damaged or broken during sampling making identification difficult. The most recently described species, Dysponetus joeli Olivier
Darbyshire, Teresa
core +3 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Journal of Marine Science and EngineeringDuring a survey of the west coast of South Korea, two new Pseudochromadora species were recorded from Yeongjongdo Island. Descriptions of two new species, an updated list of valid species within the genus, a tabular key, partial sequences of mtCOI, near ...
Hyeonggeun Kim, Raehyuk Jeong
doaj +1 more source