Results 141 to 150 of about 14,787,893 (353)
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Ecological Modelling, 2018 Among specific applications of species distribution models (SDMs), the use of SDMs probabilistic maps for guiding field surveys is increasingly applied. This approach is particularly used for poorly known and/or cryptic species in order to better assess ...
M. Fois +3 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Predicting Distributions of Invasive Species [PDF]
, 2017 28 pages, this manuscript will later be published as a book ...
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Journal of Limnology, 2014 The caddisfly Crunoecia irrorata is a wide-spread species in Europe and inhabits permanent spring areas with pristine or moderately disturbed habitat conditions.
Anna Rychła +2 more
doaj +1 more source
The Kateretidae and Nitidulidae of the Maltese Archipelago (Coleoptera) [PDF]
, 2008 In the present work, a total of 3 Kateretidae and 26 Nitidulidae are recorded from the Maltese Islands. Of these, 14 Nitidulidae (Epuraea luteola, Epuraea ocularis, Carpophilus bifenestratus, Carpophilus marginellus, Carpophilus quadrisignatus ...
Audisio, Paolo, Mifsud, David
core
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
An exactly solvable coarse-grained model for species diversity
, 2012 We present novel analytical results about ecosystem species diversity that stem from a proposed coarse grained neutral model based on birth-death processes.
Amos Maritan +8 more
core +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source