Results 81 to 90 of about 9,522,707 (252)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

How Can Overlooking Social Interactions, Space Familiarity or Other “Invisible Landscapes” Shaping Animal Movement Bias Habitat Selection Estimations and Species Distribution Predictions?

Ecology and Evolution
Species' future distributions are commonly predicted using models that link the likelihood of occurrence of individuals to the environment. Although animals' movements are influenced by physical and non‐physical landscapes, for example related to ...
Romain Dejeante, Rémi Lemaire‐Patin, Simon Chamaillé‐Jammes   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

MetaRange.jl: A Dynamic and Metabolic Species Range Model for Plant Species

Ecology and Evolution
Process‐based models for range dynamics are urgently needed due to increasing intensity of human‐induced biodiversity change. Despite a few existing models that focus on demographic processes, their use remains limited compared to the widespread ...
Jana Blechschmidt, Juliano Sarmento Cabral   +1 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Geobotanical distinction using the floristic method: example of the Polish Pomerania

Acta Societatis Botanicorum Poloniae, 2019
In the geobotanical division of Poland, Pomerania was treated as a separate subdivision, divided into “coastal plains” and the “Pomeranian uplands” or, in the newest regionalization, the “Pomeranian division”.
Maria Zając, Adam Zając, Andrzej Łysko, Agnieszka Popiela   +3 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Moving Beyond Static Species Distribution Models in Support of Conservation Biogeography [PDF]

Aim: To demonstrate that multi-modeling methods have effectively been used to combine static species distribution models (SDM), predicting the geographical pattern of suitable habitat, with dynamics landscape and population models in order to forecast ...
Janet Franklin
core  

Tree species preferences for foraging site and ways in which the preferences affect the distribution, abundance and species composition of arboreal woodland avifauna [PDF]

, 1989
The tree species preferences by six arboreal bird species and their role in structuring the bird communities in woodland were investigated in two sites in County Durham.
Peck, Kirsi Marianne
core