Results 61 to 70 of about 9,522,707 (252)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Assessing the freshwater distribution of yellow eel [PDF]

, 2008
In the global context of the decline in wild species, modeling the distribution of populations is a crucial aspect of ecological management. This can be a major challenge, especially for species, such as the European eel, that have complex life cycles ...
Lasne, Emilien, É. Lasne, P. Laffaille, Laffaille, Pascal, Laffaille P., Lasne É.   +5 more
core   +1 more source

Impact of climate change on extinction risk of montane tree species. [PDF]

, 2014
The potential impacts of climate change on many species worldwide remains unknown, especially in those tropical regions that are centers of endemism and are highly biodiverse.
Tejedor Garavito, Natalia
core   +4 more sources

An Integrative Approach to Assess and Map Zostera noltei Meadows Along the Romanian Black Sea Coast

Journal of Marine Science and Engineering
Seagrass meadows, including those formed by Zostera noltei, play a crucial role in marine ecosystem health by providing habitat stability and coastal protection. In the Romanian Black Sea, Z. noltei meadows are critically endangered due to pressures from
Oana Alina Marin, Florin Timofte, Adrian Filimon, Alina Mihaela Croitoru, Wouter van Broekhoven, Charlotte Harper, Roosmarijn van Zummeren   +6 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Invasive Species Definition Clarification and Guidance White Paper

, 2006
Paper discussing a "a non-regulatory policy interpretation of the term invasive species" through a positional defintion of what and what does not constittue an invasive species along with examples of impacts caused by invasive species.
Definitions Subcommittee of the Invasive Species Adivsory Committee
core  

Developing Species Distribution Models for Wood Turtle (Glyptemys insculpta) in Atlantic Canada

, 2022
The wood turtle, Glyptemys insculpta, is listed as threatened federally in Canada and provincially in Nova Scotia (NS) and New Brunswick (NB). Historic surveying for G.
Baker, Thomas
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source