Results 51 to 60 of about 14,653,154 (285)

A Deep Learning Approach to Species Distribution Modelling [PDF]

, 2018
Species distribution models (SDM) are widely used for ecological research and conservation purposes. Given a set of species occurrence, the aim is to infer its spatial distribution over a given territory. Because of the limited number of occurrences of specimens, this is usually achieved through environmental niche modeling approaches, i.e.
Botella, Christophe, Joly, Alexis, Bonnet, Pierre, Monestiez, Pascal, Munoz, François   +4 more
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Can species distribution models really predict the expansion of invasive species?

PLoS ONE, 2018
Predictive studies are of paramount importance for biological invasions, one of the biggest threats for biodiversity. To help and better prioritize management strategies, species distribution models (SDMs) are often used to predict the potential invasive
Morgane Barbet-Massin, Quentin Rome, Claire Villemant, Franck Courchamp   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Improving Large‐Scale Population Estimates and Assessments of the Ecological Importance of Three Epifaunal Bivalve Species by Combining Distribution and Abundance Models

Ecology and Evolution
Epifaunal bivalves include reef‐building organisms that provide several important ecological functions in coastal marine environments. Evaluating the distributional patterns and population sizes is key in assessing the total and relative contribution of ...
Youk Greeve, Molly C. Reamon, Per Bergström, Åsa Strand, Ane T. Laugen, Mats Lindegarth   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Novel methods for species distribution mapping including spatial models in complex regions [PDF]

, 2014
Species Distribution Modelling (SDM) plays a key role in a number of biological applications: assessment of temporal trends in distribution, environmental impact assessment and spatial conservation planning.
Scott-Hayward, Lindesay Alexandra Sarah
core   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Spatial confounding in joint species distribution models

Methods in Ecology and Evolution
Joint species distribution models (JSDMs) are a popular method for analysing multivariate abundance data, with important applications such as uncovering how species communities are driven by environmental processes, model‐based ordination to visualise ...
Francis K. C. Hui, Quan Vu, Mevin B. Hooten   +2 more
doaj   +1 more source