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Climate change increases the extinction risk of species, and studying the impact of climate change on endangered species is of great significance to biodiversity conservation. In this study, the endangered plant Meconopsis punicea Maxim (M.
Hao-Tian Zhang, Wen-Ting Wang
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A Deep Learning Approach to Species Distribution Modelling [PDF]
Species distribution models (SDM) are widely used for ecological research and conservation purposes. Given a set of species occurrence, the aim is to infer its spatial distribution over a given territory. Because of the limited number of occurrences of specimens, this is usually achieved through environmental niche modeling approaches, i.e.
Botella, Christophe +4 more
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The increasing use of species distribution modeling (SDM) has raised new concerns regarding the inaccuracies, misunderstanding, and misuses of this important tool.
P. De Marco, C. Nóbrega
semanticscholar +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
IntroductionClimate change represents an escalating threat to wildlife globally, disrupting ecosystems and altering species interactions. Key nut-producing forest species in the Cantabrian Mountains may be affected, with consequences for Cantabrian brown
José Carlos Pérez-Girón +3 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Current and Future Habitat Suitability Models for Four Ticks of Medical Concern in Illinois, USA
The greater U.S. Midwest is on the leading edge of tick and tick-borne disease (TBD) expansion, with tick and TBD encroachment into Illinois occurring from both the northern and the southern regions.
Heather L. Kopsco +3 more
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Hierarchical Species Distribution Models [PDF]
Determining the distribution pattern of a species is important to increase scientific knowledge, inform management decisions, and conserve biodiversity. To infer spatial and temporal patterns, species distribution models have been developed for use with many sampling designs and types of data.
Trevor J. Hefley, Mevin B. Hooten
openaire +1 more source

