Results 81 to 90 of about 14,653,154 (285)
Ecological InformaticsSpecies distribution models are widely used in ecology and conservation biology to predict species' habitat suitability, but their performance is often compromised by biases in occurrence data.
Rocìo Beatriz Cortès Lobos +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Inferring the similarity of species distributions using Species’ Distribution Models
Ecography, 2013 A common problem in ecology is our need to reliably compare information on the distributions of distinct species. Since it is not always possible to directly compare the distributions of two species, numerous papers now seek to compare the predictions of Species’ Distribution Models (SDMs, estimates of the probability that two species are present ...
openaire +2 more sources
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Variation in Spatial Predictions Among Species Distribution Modeling Methods [PDF]
Prediction maps produced by species distribution models (SDMs) influence decision-making in resource management or designation of land in conservation planning. Many studies have compared the prediction accuracy of different SDM modeling methods, but few
Alexandra D. Syphard, Janet Franklin
core
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Improving species distribution models for invasive non‐native species with biologically informed pseudo‐absence selection [PDF]
, 2019 Aim: We present a novel strategy for species distribution models (SDMs) aimed at predicting the potential distributions of range‐expanding invasive non‐native species (INNS).
Pescott, Oliver L. +9 more
core +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Environmental factors influencing the distribution of bats (Chiroptera) in South Africa [PDF]
, 2012 Environmental factors limiting the distribution of 37 of the 56 bat species in a warm temperate region (South Africa) were determined using GIS software and the Maximum Entropy modelling technique (MaxEnt).
Salata, Hassan Aburaida Babiker
core +1 more source
Impact of climate change on extinction risk of montane tree species. [PDF]
, 2014 The potential impacts of climate change on many species worldwide remains unknown, especially in those tropical regions that are centers of endemism and are highly biodiverse.
Tejedor Garavito, Natalia
core +4 more sources