Results 51 to 60 of about 755,136 (266)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
MycobiologyPichia species are widely distributed across various ecosystems and have industrial significance, particularly in wine fermentation and bioproduct synthesis.
Chorong Ahn +3 more
doaj +1 more source
A new species of Ditha (Pseudoscorpiones, Chthoniidae, Tridenchthoniinae) from the Western Ghats of India, with an identification key for the genus [PDF]
Zoosystematics and EvolutionA new species of the pseudoscorpion genus Ditha Chamberlin, 1929, is described from Kerala State, India. A detailed morphological description, diagnostic features, and illustrations of Ditha (Paraditha) shivanparaensis Jeong, Harms & Johnson, sp.
Kyung-Hoon Jeong +2 more
doaj +3 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
• The species composition in Swiss forests is changing. While ash and sweet chestnut have declined, there have been increases in maple and Arolla pine and in the average number of moss and gastropod species.• Around 40% of Switzerland’s animal and plant species live in forests, with the proportion of forest-dwelling species particularly high among ...
Bollmann, Kurt +3 more
openaire +3 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Species Diversity--Scale Matters
Science, 2002 The marked gradient in species diversity between the equator (where it is highest) and the poles (where it is lowest) suggests a simple environmental explanation for this phenomenon. However, as Willis and Whittaker point out in their Perspective, the environmental variables driving species diversity are different depending on the size and time
Willis, K, Whittaker, R
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Partitioning genetic and species diversity refines our understanding of species–genetic diversity relationships [PDF]
Ecology and Evolution, 2018 AbstractDisentangling the origin of species–genetic diversity correlations (SGDCs) is a challenging task that provides insight into the way that neutral and adaptive processes influence diversity at multiple levels. Genetic and species diversity are comprised by components that respond differently to the same ecological processes.
Pfeiffer, Vera Wilder +7 more
openaire +5 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Frontiers in Plant Science, 2017 The teosinte branched1/cycloidea/proliferating cell factor (TCP) gene family is a plant-specific transcription factor that participates in the control of plant development by regulating cell proliferation.
Jiancan Du +16 more
doaj +1 more source