Results 61 to 70 of about 755,136 (266)
The Magnitude of Global Marine Species Diversity [PDF]
Background: The question of how many marine species exist is important because it provides a metric for how much we do and do not know about life in the oceans. We have compiled the first register of the marine species of the world and used this baseline to estimate how many more species, partitioned among all major eukaryotic groups, may be discovered.
Appeltans, Ward +120 more
openaire +8 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Background Robust phylogenies for species with giant genomes and closely related taxa can build evolutionary frameworks for investigating the origin and evolution of these genomic gigantisms. Paris japonica (Melanthiaceae) has the largest genome that has
Lifang Yang +8 more
doaj +1 more source
Species diversity, functional diversity, and ecosystem functioning
Abstract Experiments assessing the effects of biodiversity on ecosystem functioning initially aimed at establishing whether such relationships exist (e.g. Naeem et al. 1995; Tilman et al. 1996; Jonsson and Malmqvist 2000; Engelhardt and Ritchie 2001).
Hooper, D.U. +12 more
openaire +3 more sources
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Biocontrol Potential of Streptomyces sp. C2-4 against Ceratobasidium cereale Caused Sharp Eyespot in Wheat [PDF]
Recently, various fungal diseases have emerged in winter crops, including barley, oats, and wheat, as a consequence of climate change. Among these diseases, sharp eyespot, caused by Ceratobasidium cereale, is a significant concern because it occurs ...
Miju Jo +4 more
doaj +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Adelphomyia crane flies (Diptera, Limoniidae) of Korea with identification key for all Palaearctic species [PDF]
Limnophilinae crane flies belonging to the genus Adelphomyia Bergroth, 1891 of the Korean Peninsula were studied starting from 1937, but only one species A. macrotrichiata (Alexander, 1923) has been recorded from North Korea so far. The genus was unknown
Sigitas Podenas +2 more
doaj +3 more sources
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source

