Results 81 to 90 of about 6,677,400 (360)

Quantification of mesocosm fish and amphibian species diversity via environmental DNA metabarcoding

Molecular Ecology Resources, 2015
Freshwater fauna are particularly sensitive to environmental change and disturbance. Management agencies frequently use fish and amphibian biodiversity as indicators of ecosystem health and a way to prioritize and assess management strategies ...
Nathan T. Evans, Brett P. Olds, M. Renshaw, C. Turner, Yiyuan Li, C. Jerde, A. Mahon, M. Pfrender, G. Lamberti, D. Lodge   +9 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Transcriptome data analysis provides insights into the conservation of Michelia lacei, a plant species with extremely small populations distributed in Yunnan province, China

BMC Plant Biology
Background Michelia lacei W.W.Smith (Magnoliaceae), was classified as a Plant Species with Extremely Small Populations (PSESP) by the Yunnan Provincial Government in both action plans of 2012 and 2021. This evergreen tree is known for its high ornamental
Yang Liu, Lei Cai, Weibang Sun
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Two near-chromosomal-level genomes of globally-distributed Macroascomycete based on single-molecule fluorescence and Hi-C methods

Scientific Data
Discinaceae holds significant importance within the Pezizales, representing a prominent group of macroascomycetes distributed globally. However, there is a dearth of genomic studies focusing on this family, resulting in gaps in our understanding of its ...
Wei Liu, Xiaofei Shi, Yingli Cai, Wenhua Sun, Peixin He, Jesus Perez-Moreno, Dong Liu, Fuqiang Yu   +7 more
doaj   +1 more source

Loss of Plant Species Diversity Reduces Soil Erosion Resistance

Ecosystems, 2015
In many estuarine areas around the world, the safety of human societies depends on the functioning of embankments (dikes) that provide protection against river floods and storm tides. Vegetation on land-side slopes protects these embankments from erosion
F. Berendse, J. Ruijven, E. Jongejans, S. Keesstra   +3 more
semanticscholar   +1 more source

High Malaria Mosquito Species Diversity, Their Blood Feeding Patterns, Role in Malaria Transmission and The Challenge of Morphological Classification: An Implication for Entomological Surveillance and Monitoring, Southwestern Ethiopia

, 2022
Adilo Assa, Nigatu Eligo, Fekadu Massebo
openalex   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Plastid Genome Evolution in the Early-Diverging Legume Subfamily Cercidoideae (Fabaceae)

Frontiers in Plant Science, 2018
The subfamily Cercidoideae is an early-branching legume lineage, which consists of 13 genera distributed in the tropical and warm temperate Northern Hemisphere.
Yin-Huan Wang, Yin-Huan Wang, Yin-Huan Wang, Susann Wicke, Hong Wang, Jian-Jun Jin, Jian-Jun Jin, Si-Yun Chen, Shu-Dong Zhang, De-Zhu Li, De-Zhu Li, Ting-Shuang Yi, Ting-Shuang Yi   +12 more
doaj   +1 more source