Results 161 to 170 of about 7,579,699 (309)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Across species identification of genes bridging neurological and reproductive functions in mammals. [PDF]

iScience
Kizilaslan Z, Graybeal JT, Huffman C, Montoya AM, Peñagaricano F, Kizilaslan M, Ahsan N, Khatib H.   +7 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Cross-species identification of conserved and divergent locomotor kinematic strategies using AutoGaitA. [PDF]

Proc Natl Acad Sci U S A
Hosseini M, Klein I, Wunderle V, Haustein M, Semmler C, Kramer AK, Tolve M, Mardare V, Galvao A, Kuzu TD, Grefkes C, Korotkova T, Büschges A, Fink GR, Weiss PH, Daun S, Gatto G.   +16 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

PCR-based species identification tools for wireworms (Coleoptera: Elateridae) of economic importance in Canada. [PDF]

Pest Manag Sci
Furtado K, van Herk WG, Cheema SK, Ritland CE, Hamelin RC, Franklin MT.   +5 more
europepmc   +1 more source

Web Check in Ohio

, 2007
Title from cover of PDF document (viewed Dec. 13, 2007).; "Created: 1/18/2006 ...; Modified: 1/1/2007"--Document properties screen.; Harvested from the web on 12/13 ...
Ohio Bureau of Criminal Identification & Investigation.
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Forensic Species Identification: A Case Involving Trafficked Fish Maws and Shark Fins. [PDF]

Int J Mol Sci
Li H, Chu X, Xiao W, Jiang J, Xia R, Chen M, Di Y, Liu Y, Liu X.   +8 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source