Results 51 to 60 of about 484,876 (307)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

The relationship between elevation and seed-plant species richness in the Mt. Namjagbarwa region (Eastern Himalayas) and its underlying determinants

Global Ecology and Conservation, 2020
Understanding how species richness changes along altitudinal gradients and what mechanisms answer for those patterns has intrigued increasing attention from numerous researchers, however, there is still no consistent agreement on these questions.
Lu Sun, Jian Luo, Lishen Qian, Tao Deng, Hang Sun   +4 more
doaj   +1 more source

Conservation-relevant plant species indicate arthropod richness across trophic levels: Habitat quality is more important than habitat amount

Ecological Indicators, 2023
The massive declines in terrestrial arthropods reported across Europe call for effective methods to monitor and promote biodiversity in human-dominated landscapes.
Cynthia Tobisch, Sandra Rojas-Botero, Johannes Uhler, Johannes Kollmann, Jörg Müller, Christoph Moning, Sarah Redlich, Ingolf Steffan-Dewenter, Caryl Benjamin, Jana Englmeier, Ute Fricke, Cristina Ganuza, Maria Haensel, Rebekka Riebl, Lars Uphus, Jörg Ewald   +15 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Emerging patterns of species richness, diversity, population density, and distribution in the skates (Rajidae) of Alaska [PDF]

, 2008
Six years of bottom-trawl survey data, including over 6000 trawls covering over 200 km2 of bottom area throughout Alaska’s subarctic marine waters, were analyzed for patterns in species richness, diversity, density, and distribution of skates. The Bering
Hoff, Gerald R., McEachran, John D., Orr, James W., Stevenson, Duane E.   +3 more
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Beyond Species Richness for Biological Conservation

Conservation Letters
Recent global policy developments have highlighted the need for straightforward, robust, and meaningful biodiversity metrics. However, much of conservation science is dominated by the use of a single metric, species richness, despite several known ...
Robert J. Fletcher Jr., Rhys E. Green, Eleanor K. Bladon, Philip W. Atkinson, Benjamin T. Phalan, David Williams, Piero Visconti, Andrew Balmford   +7 more
doaj   +1 more source

Comparison of species richness of light trap-collected caddisfly assemblages (Insecta: Trichoptera) using rarefaction [PDF]

, 2002
ConselVation value of light trap-collected caddisfly assemblages(Insecta: Trichoptera) was evaluated on the basis of their species richness. The assemblage coming from an artificial stream showed a higher conservation value based on species richness than
Schmera, Dénes
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Mapping Potential Plant Species Richness over Large Areas with Deep Learning, MODIS, and Species Distribution Models

Remote Sensing, 2021
The spatial patterns of species richness can be used as indicators for conservation and restoration, but data problems, including the lack of species surveys and geographical data gaps, are obstacles to mapping species richness across large areas.
Hyeyeong Choe, Junhwa Chi, James H. Thorne   +2 more
doaj   +1 more source