Results 61 to 70 of about 482,058 (353)

Comparison of species richness of light trap-collected caddisfly assemblages (Insecta: Trichoptera) using rarefaction [PDF]

open access: yes, 2002
ConselVation value of light trap-collected caddisfly assemblages(Insecta: Trichoptera) was evaluated on the basis of their species richness. The assemblage coming from an artificial stream showed a higher conservation value based on species richness than
Schmera, Dénes
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

More endemic birds occur in regions with stable climate, more plant species and high altitudinal range in China

open access: yesAvian Research, 2020
Background Geographical distribution of endemic species and its multiple scale drivers are an important topic in biodiversity conservation, because these species are especially vulnerable to climate change and habitat degradation, and therefore have high
Gang Feng   +5 more
doaj   +1 more source

Emerging patterns of species richness, diversity, population density, and distribution in the skates (Rajidae) of Alaska [PDF]

open access: yes, 2008
Six years of bottom-trawl survey data, including over 6000 trawls covering over 200 km2 of bottom area throughout Alaska’s subarctic marine waters, were analyzed for patterns in species richness, diversity, density, and distribution of skates. The Bering
Hoff, Gerald R.   +3 more
core  

Bees (Hymenoptera: Apoidea) of the Chicago Area: Diversity and Habitat Use in an Urbanized Landscape [PDF]

open access: yes, 2018
Bees (Hymenoptera: Apoidea) were collected at 24 sites chosen to represent the diversity of urban and natural habitats in the Chicago metropolitan area. Species richness was assessed for each site.
Molumby, Alan, Przybylowicz, Tomasz
core   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Beyond Species Richness for Biological Conservation

open access: yesConservation Letters
Recent global policy developments have highlighted the need for straightforward, robust, and meaningful biodiversity metrics. However, much of conservation science is dominated by the use of a single metric, species richness, despite several known ...
Robert J. Fletcher Jr.   +7 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

The relationship between elevation and seed-plant species richness in the Mt. Namjagbarwa region (Eastern Himalayas) and its underlying determinants

open access: yesGlobal Ecology and Conservation, 2020
Understanding how species richness changes along altitudinal gradients and what mechanisms answer for those patterns has intrigued increasing attention from numerous researchers, however, there is still no consistent agreement on these questions.
Lu Sun   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy