Results 61 to 70 of about 484,876 (307)
Distinct or similar? Soft bottom polychaete diversity in Arctic and Antarctic glacial fjords [PDF]
, 2014 The main aim of this study was to compare the polychaete communities in two similar polar areas: an Arctic fjord, Hornsund (Svalbard) and an Antarctic fjord, Ezcurra Inlet (South Shetlands).
Gromisz, Sławomira +2 more
core +2 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Reserve Size And Fragmentation Alter Community Assembly, Diversity, And Dynamics [PDF]
, 2013 Researchers have disputed whether a single large habitat reserve will support more species than many small reserves. However, relatively little is known from a theoretical perspective about how reserve size affects competitive communities structured by ...
Keitt, Timothy H., Lasky, Jesse R.
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Bees (Hymenoptera: Apoidea) of the Chicago Area: Diversity and Habitat Use in an Urbanized Landscape [PDF]
, 2018 Bees (Hymenoptera: Apoidea) were collected at 24 sites chosen to represent the diversity of urban and natural habitats in the Chicago metropolitan area. Species richness was assessed for each site.
Molumby, Alan, Przybylowicz, Tomasz
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Global Ecology and ConservationThe ongoing loss of species diversity highlights necessitates elucidating the drivers of species richness to inform biodiversity conservation and sustainable forest management strategies.
Jianfeng Li +4 more
doaj +1 more source
Experimental Manipulation of Grassland Plant Diversity Induces Complex Shifts in Aboveground Arthropod Diversity. [PDF]
PLoS ONE, 2016 Changes in producer diversity cause multiple changes in consumer communities through various mechanisms. However, past analyses investigating the relationship between plant diversity and arthropod consumers focused only on few aspects of arthropod ...
Lionel R Hertzog +3 more
doaj +1 more source
Spiders (Araneae) from Agricultural fields near foothill of Satpura Mountain ranges of Amravati District, Maharashtra, India. [PDF]
, 2011 This paper deals with the study of spider distribution in agricultural fields adjoining the Satpura Mountain Ranges of the Amravati district. The total collection of spiders comprises 12 families, 37 genera and 76 species.
Anil J. Gaur +5 more
core +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source