Results 111 to 120 of about 354,259 (294)
FEBS Open Bio, EarlyView.We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
Factors limiting sand dune restoration in Northwest Beach, Point Pelee National Park, Canada [PDF]
, 2018 Known as home to rare species of flora and fauna, and their critical habitats, Northwest beach of Point Pelee National Park has undergone significant ecological and infrastructural changes in the past decades.
Nayak, Pritichhanda +1 more
core +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Resolution among major placental mammal interordinal relationships with genome data imply that speciation influenced their earliest radiations [PDF]
, 2010 Background: A number of the deeper divergences in the placental mammal tree are still inconclusively resolved despite extensive phylogenomic analyses.
Hallström, Björn M., Janke, Axel
core
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes
eLife, 2019 Extracellular vesicles (EVs) encompass a variety of vesicles secreted into the extracellular space. EVs have been implicated in promoting tumor metastasis, but the molecular composition of tumor-derived EV sub-types and the mechanisms by which molecules ...
Morayma M Temoche-Diaz +6 more
doaj +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Sorting Models in Discrete Choice Fisheries Analysis [PDF]
One of the greatest challenges facing empirical fisheries researchers is to endogenize fishing effort in bioeconomic models in a way that accounts for fleet heterogeneity.
Smith, Martin D., Zhang, Junjie
core +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Automatic Mackerel Sorting Machine Using Global and Local Features
IEEE Access, 2019 In Japan, blue and chub mackerels are often caught simultaneously, and their market prices are different. Humans need to sort them manually, which requires heavy labor. The demand for automatic sorting machines is increasing.
Yoshito Nagaoka +3 more
doaj +1 more source