Results 111 to 120 of about 744,887 (310)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Comparative genomics of plant pathogenic Botrytis species with distinct host specificity

BMC Genomics, 2019
Background Fungi of the genus Botrytis (presently containing ~ 35 species) are able to infect more than 1400 different plant species and cause losses in a wide range of crops of economic importance. The best studied species is B.
Claudio A. Valero-Jiménez, Javier Veloso, Martijn Staats, Jan A. L. van Kan   +3 more
doaj   +1 more source

Ergasilid copepods and grey mullet

, 1999
PhDThe parasitic copepod family Ergasilidae currently comprises 26 genera and more than 180 species, the great majority of which utilises marine, brackish and freshwater fishes as hosts.
El-Rashidy, Hoda Hassan
core  

Species specificity of PCR for H. pylori.

, 2013
Species specificity of PCR for H. pylori.
Xavier Calvet (70152), Sergio Lario (351188), Jordi Sánchez-Delgado (351193), Maria Rosa Bella-Cueto (351195), Isabel Sanfeliu (351196), Loreto Boix (351191), Esther Sanfeliu (351190), Alex Casalots (351189), Marta Gallach (342508), María José Ramírez-Lázaro (351187), Ferran Segura (351197), Pilar García-Iglesias (351192), Antònia Montserrat (351194)   +12 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Comparative Pathogenicity and Host Ranges of Magnaporthe oryzae and Related Species

The Plant Pathology Journal, 2020
Host shifting and host expansion of fungal plant pathogens increases the rate of emergence of new pathogens and the incidence of disease in various crops, which threaten global food security. Magnaporthe species cause serious disease in rice, namely rice
doaj   +1 more source

Patterns of interaction specificity of fungus-growing termites and Termitomyces symbionts in South Africa

BMC Evolutionary Biology, 2007
Background Termites of the subfamily Macrotermitinae live in a mutualistic symbiosis with basidiomycete fungi of the genus Termitomyces. Here, we explored interaction specificity in fungus-growing termites using samples from 101 colonies in South-Africa ...
de Beer Z Wilhelm, Mitchell Jannette, de Fine Licht Henrik H, Ros Vera ID, Aanen Duur K, Slippers Bernard, Rouland-LeFèvre Corinne, Boomsma Jacobus J   +7 more
doaj   +1 more source

Comparative host specificity of human- and pig- associated Staphylococcus aureus clonal lineages.

, 2012
Bacterial adhesion is a crucial step in colonization of the skin. In this study, we investigated the differential adherence to human and pig corneocytes of six Staphylococcus aureus strains belonging to three human-associated [ST8 (CC8), ST22 (CC22) and ...
Moodley, Arshnee, Moodley Arshnee, Moodley, A, Guardabassi Luca, Espinosa-Gongora, Carmen, Arshnee Moodley, Søren S Nielsen, Espinosa-Gongora Carmen, Nielsen, Søren Saxmose, McCarthy Alex J., McCarthy, AJ, Lindsay, JA, Lindsay, Jodi A., Guardabassi, Luca, Guardabassi, L, Jodi A Lindsay, McCarthy, Alex J., Lindsay Jodi A., Nielsen, SS, Luca Guardabassi, Nielsen Søren S., Espinosa-Gongora, C, Carmen Espinosa-Gongora, Alex J McCarthy   +23 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Sequence similarity is more relevant than species specificity in probabilistic backtranslation

BMC Bioinformatics, 2007
Background Backtranslation is the process of decoding a sequence of amino acids into the corresponding codons. All synthetic gene design systems include a backtranslation module.
Di Pietro Cinzia, Pulvirenti Alfredo, Pigola Giuseppe, Giugno Rosalba, Ferro Alfredo, Purrello Michele, Ragusa Marco   +6 more
doaj   +1 more source