Biological control of Rubus alceifolius (Rosaceae) in La Réunion Island (Indian Ocean): from investigations of the plant to the release of the biocontrol agent Cibdela janthina (Argidae) [PDF]
, 2011 The giant bramble (Rubus alceifolius Poir.: Rosaceae), native to Southeast Asia, is one of the most invasive plants in La Réunion. A ten year research program was launched in 1997 with three components: i) genetic diversity, ii) development strategy, and
Baret, Stéphane +2 more
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Mating pair stabilization mediates bacterial conjugation species specificity. [PDF]
Nat Microbiol, 2022 Low WW +14 more
europepmc +1 more source
The Stability of Mean Wood Specific Gravity across Stand Age in US Forests Despite Species Turnover [PDF]
, 2019 Sean P. Healey, James Menlove
openalex +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Development of Specific Monoclonal Antibodies against Porcine RIG-I-like Receptors Revealed the Species Specificity. [PDF]
Int J Mol Sci, 2023 Shao Q +10 more
europepmc +1 more source
[Species-specific primate husbandry].
DTW. Deutsche tierarztliche Wochenschrift, 2005 With about 300 species primates represent one of the largest animal groups within mammals. They are kept in zoological gardens, as laboratory animals or in private ownership. Against this background it is difficult to define all species-specific aspects of a primate husbandry.
openaire +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Determinants of Species Specificity of α-Conotoxin TxIB towards Rat and Human α6/α3β4 Nicotinic Acetylcholine Receptors. [PDF]
Int J Mol Sci, 2023 Xie T +9 more
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source