Results 131 to 140 of about 13,239,264 (387)

Isoform‐specific modification of apolipoprotein E by 4‐hydroxynonenal: protective role of apolipoprotein E3 against oxidative species

, 2023
Muhammad I. Abeer, Abbas Abdulhasan, Zahraa Haguar, Vasanthy Narayanaswami   +3 more
openalex   +2 more sources

Exploring Species-Specificity in TLR4/MD-2 Inhibition with Amphiphilic Lipid A Mimicking Glycolipids. [PDF]

Molecules, 2023
Borio A, Holgado A, Passegger C, Strobl H, Beyaert R, Heine H, Zamyatina A.   +6 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Species-Specific Valid Ternary Interactions of HIV-1 Env-gp120, CD4, and CCR5 as Revealed by an Adaptive Single-Amino Acid Substitution at the V3 Loop Tip

, 2021
Takaaki Koma, Masaru Yokoyama, Osamu Kotani, Naoya Doi, Nina Nakanishi, Hayato Okubo, Shun Adachi, Akio Adachi, Hironori Sato, Masako Nomaguchi   +9 more
openalex   +2 more sources

De Novo Assembly and Species-Specific Marker Development as a Useful Tool for the Identification of Scutellaria L. Species [PDF]

, 2021
Hakjoon Choi, Wan Seok Kang, Jin Seok Kim, Chang-Su Na, Sunoh Kim   +4 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Tissue-specific and species-specific esterases [PDF]

Biochemical Journal, 1961
J, PAUL, P, FOTTRELL
openaire   +2 more sources

Development of Specific Monoclonal Antibodies against Porcine RIG-I-like Receptors Revealed the Species Specificity. [PDF]

Int J Mol Sci, 2023
Shao Q, Li S, Cao Q, Gu H, Zhang J, Zhang Y, Zhang K, Zheng W, Chen N, Shang S, Zhu J.   +10 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Isotype conversion of Staphylococcal-specific IgG into IgM broadens the reactivity to other bacterial pathogens

Cell Reports Medicine
Summary: Therapeutic antibodies are actively explored as alternative to treat or prevent bacterial infections. However, the narrow antigen specificity of IgG in combination with broad diversity in bacterial surface structures currently hampers the ...
Remy M. Muts, Astrid Hendriks, Josefien W. Hommes, Max L.B. Grönloh, Douwe J. Dijkstra, Carla J.C. de Haas, Piet C. Aerts, Eduard H.T.M. Ebberink, Albert J.R. Heck, Zhen Wang, Haoru Zhuang, Jeroen D.C. Codée, Bas G.J. Surewaard, Dani A.C. Heesterbeek, Nina M. van Sorge, Suzan H.M. Rooijakkers   +15 more
doaj   +1 more source