Results 151 to 160 of about 13,028,141 (393)

Exploring Species-Specificity in TLR4/MD-2 Inhibition with Amphiphilic Lipid A Mimicking Glycolipids. [PDF]

Molecules, 2023
Borio A, Holgado A, Passegger C, Strobl H, Beyaert R, Heine H, Zamyatina A.   +6 more
europepmc   +1 more source

Specificity of soil-borne pathogens on grain legumes [PDF]

, 2004
Specificity of soil-borne legume pathogens on pea, lupin and faba bean is currently investigated in fields where grain legumes are intensively cultivated.
Bødker, Lars, Jensen, Birgit, Jørnsgaard, Bjarne, Knudsen, Jens Chr., Larsen, John   +4 more
core  

Capacitation of Rabbit Spermatozoa: Species Specificity and Organ Specificity.

Experimental Biology and Medicine, 1967
SummaryIt has been found that washed rabbit sperm may be capacitated in the uterus of an estrous rabbit, rat, and dog, indicating that the capacitation mechanism is similar in these species. It was shown that washed rabbit sperm are capacitated only in the uterus and oviduct of the estrous rabbit and not in the bladder, colon and knee joint, indicating
Nickolas J. Sojka, Charles E. Hamner
openaire   +3 more sources

CKSP: Cross-species Knowledge Sharing and Preserving for Universal Animal Activity Recognition [PDF]

arXiv
Deep learning techniques are dominating automated animal activity recognition (AAR) tasks with wearable sensors due to their high performance on large-scale labelled data. However, current deep learning-based AAR models are trained solely on datasets of individual animal species, constraining their applicability in practice and performing poorly when ...
arxiv  

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

The reconstructed tree in the lineage-based model of protracted speciation [PDF]

arXiv, 2013
A popular line of research in evolutionary biology is the use of time-calibrated phylogenies for the inference of diversification processes. This requires computing the likelihood of a given ultrametric tree as the reconstructed tree produced by a given model of diversification.
arxiv  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Development of Specific Monoclonal Antibodies against Porcine RIG-I-like Receptors Revealed the Species Specificity. [PDF]

Int J Mol Sci, 2023
Shao Q, Li S, Cao Q, Gu H, Zhang J, Zhang Y, Zhang K, Zheng W, Chen N, Shang S, Zhu J.   +10 more
europepmc   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Molecular Determinants of Species Specificity of α-Conotoxin TxIB towards Rat and Human α6/α3β4 Nicotinic Acetylcholine Receptors. [PDF]

Int J Mol Sci, 2023
Xie T, Qin Y, Zhao J, Dong J, Qi P, Zhang P, Zhangsun D, Zhu X, Yu J, Luo S.   +9 more
europepmc   +1 more source