Identification of plasma lipid biomarkers for prostate cancer by lipidomics and bioinformatics [PDF]
Background: Lipids have critical functions in cellular energy storage, structure and signaling. Many individual lipid molecules have been associated with the evolution of prostate cancer; however, none of them has been approved to be used as a ...
AA Elgamal +58 more
core +10 more sources
Analysis of Porcine RIG-I Like Receptors Revealed the Positive Regulation of RIG-I and MDA5 by LGP2
The RLRs play critical roles in sensing and fighting viral infections especially RNA virus infections. Despite the extensive studies on RLRs in humans and mice, there is a lack of systemic investigation of livestock animal RLRs.
Shuangjie Li +49 more
doaj +1 more source
Conformational adaptation of Asian macaque TRIMCyp directs lineage specific antiviral activity [PDF]
TRIMCyps are anti-retroviral proteins that have arisen independently in New World and Old World primates. All TRIMCyps comprise a CypA domain fused to the tripartite domains of TRIM5α but they have distinct lentiviral specificities, conferring HIV-1 ...
A Katzourakis +62 more
core +9 more sources
Fracture healing is highly dependent on an early inflammatory response in which prostaglandin production by cyclo-oxygenases (COX) plays a crucial role.
L. Henry Goodnough +12 more
doaj +1 more source
The Incompetence of Mosquitoes—Can Zika Virus Be Adapted To Infect Culex tarsalis Cells?
The molecular evolutionary mechanisms underpinning virus-host interactions are increasingly recognized as key drivers of virus emergence, host specificity, and the likelihood that viruses can undergo a host shift that alters epidemiology and transmission
Emily N. Gallichotte +8 more
doaj +1 more source
On the Species Specificity of Acceptor RNA and Attachment Enzymes [PDF]
One of the steps in protein biosynthesis appears to be the attachment of each amino acid to a specific acceptor (SRNA) molecule. According to the adaptor hypothesis, each SRNA molecule would then fit to a specific complementary base sequence on a linear ...
Benzer, Seymour, Weisblum, Bernard
core +2 more sources
Bovine enteric bacterial pathogens are a major cause of health decline in agricultural cattle populations. The identification of host-derived microbiota with probiotic characteristics is key for the development of treatments utilizing pathogen ...
Wen-Chin Lin +7 more
doaj +1 more source
Increased sampling reveals novel lineages of Entamoeba: consequences of genetic diversity and host specificity for taxonomy and molecular detection. [PDF]
To expand the representation for phylogenetic analysis, ten additional complete Entamoeba small-subunit rRNA gene sequences were obtained from humans, non-human primates, cattle and a tortoise. For some novel sequences no corresponding morphological data
Alfellani, Mohammed +7 more
core +1 more source
Insights Into a Chlamydia pneumoniae-Specific Gene Cluster of Membrane Binding Proteins
Chlamydia pneumoniae is an obligate intracellular pathogen that causes diseases of the upper and lower respiratory tract and is linked to a number of severe and chronic conditions. Here, we describe a large, C.
Corinna Braun +2 more
doaj +1 more source
Epiparasitic plants specialized on arbuscular mycorrhizal fungi [PDF]
Over 400 non-photosynthetic species from 10 families of vascular plants obtain their carbon from fungi and are thus defined as myco-heterotrophs. Many of these plants are epiparasitic on green plants from which they obtain carbon by 'cheating' shared ...
AH Fitter +38 more
core +2 more sources

