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Species Specificity in Fertilization
1974In his classical monograph, Problems of Fertilization, Lillie (1919) devoted a chapter to the problem of specificity in fertilization which, nearly 40 years later, Rothschild (1956) commended to all students of fertilization. In summing up his own chapter on “Specificity”, Rothschild considered the only advances to have been made since Lillie’s ...
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“Species Specificity” of Interferons: a Misnomer?
Nature, 1967IN 1961, there were two reports of monkey interferon protecting human cells1,2 and one of human interferon protecting monkey cells3, but in none of these was the oxtent of the cross-reaction measured. In view of the usual strict “species specificity” of iiiterferons (for example, chick interferon is not active in mouse cells, human cells4 or duck ...
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The liver specific protein: evidence for species-specific and non-species-specific determinants.
Journal of clinical & laboratory immunology, 1980Liver specific protein (LSP) is known to be a macrolipoprotein of complete organ-specificity but without complete species-specificity. This membrane antigen is believed to play an important role in the pathogenesis of human and experimental chronic active hepatitis (CAH).
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Species Specificity of Organ Toxicity
1995The species specificity of target organ toxicity has been the basis for the understanding of toxic mechanism and development of new active chemicals in the areas of pharmaceutics and agrochemicals. The demonstration of selective toxicity is evident in comparative studies in both animals and plants.
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Species Specificity in Nitrosamine Carcinogenesis
1983Many types of carcinogens show pronounced differences in effect in different species, often inducing tumors of a certain site in one and being inactive in another. N-Nitroso compounds, on the other hand, are commonly carcinogenic in all species examined, but induce tumors of different cell types and in different organs from one species to the next ...
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Species specificity in serum albumins
Comparative Biochemistry and Physiology, 1963Abstract 1. 1. The serum albumins of six mammalian species have been studied by methods which permit comparison of their primary structure. 2. 2. Chromatograms of the peptides produced by tryptic digestion of performate-oxidized proteins revealed patterns indicating major species differences. 3. 3.
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Species-specific proteins in fossils
Naturwissenschaften, 1980With a solid-phase radioimmunoassay it has been possible to detect species-specific collagen and albumin fossils as old as 1.9 million years. This technique may provide new data on the genetic relations of fossil species to each other and to living forms.
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Species Specificity of Fibrinogens
The Journal of Immunology, 1933Abstract Introduction. The selectivity with which antibodies react with the particular proteins used in their production affords a biological method of differentiating proteins which is far more delicate than that of direct chemical analysis.
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