Results 121 to 130 of about 4,755,677 (326)
Sokak Hayvanlarının Medyada Ötekileştirici Temsili Üzerine Bir Tematik Analiz
İletişim Kuram ve Araştırma DergisiTürcülük, insan-merkezli bir hiyerarşi kurarak insan dışı canlılar olan hayvanları alt sınıflara yerleştiren, onları toplumsal, hukuki ve ahlaki açıdan değersizleştiren bir ötekileştirme biçimi olarak tanımlanmaktadır.
Çağla Daşcı
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
TAHAKKÜMÜN MUHAKEMESİ: İHVÂN-I SAFÂ’DA HAYVANLARIN ÖZGÜRLEŞME MÜCADELESİ
İslami İlimler Dergisiİslam düşüncesinde hayvan etiğiyle alakalı karşımıza çıkan en dikkat çekici metinlerden biri, İhvân-ı Safâ Risâleleri’nin “Hayvanların Yaratılışının Keyfiyeti ve Onların Sınıfları Üzerine” başlıklı yirmi ikinci risâlesidir.
Abdullah Özkan
doaj +1 more source
The Immorality of Eating Meat [PDF]
, 2000 Unlike other ethical arguments for veganism, the argument advanced is not predicated on the wrongness of speciesism, nor does it depend on your believing that all animals are equal or that all animals have a right to life, nor is it predicated on some ...
Engel, Mylan
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Were Neanderthals Rational? A Stoic Approach
Humanities, 2018 This paper adopts the philosophical approach of Stoicism as the basis for re-examining the cognitive and ethical relationship between Homo sapiens and Neanderthals.
Kai Whiting +3 more
doaj +1 more source
Children and Pets: The Hidden Victims of Domestic Violence & Abuse (DVA): Where Action & Activism merge! [PDF]
, 2019 Children and Pets: The Hidden Victims of Domestic Violence & Abuse (DVA): Where Action & Activism merge! Researchers such as Harne (2011) and Radford et al (2011) have long championed the area of Children’s rights in the DVA field and the Government ...
McKie, Ruth, Turgoose, Di
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Rural-urban dynamics in the UK illegal puppy trade: Trafficking and trade in 'man's best friend' [PDF]
, 2019 Recently, much attention has been given to the presence and increase of transnational crime, particularly focusing on online illicit markets. A seldom-explored aspect of transnational online illicit markets is the rural to urban flow of the illicit goods.
Maher, Jennifer A, Wyatt, Tanya
core +2 more sources
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source