Results 131 to 140 of about 4,755,677 (326)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Darwin, Victorian Literature, and the Great Web: Analyzing and Dismantling the Human Superiority Complex [PDF]
, 2011 In my essay, I will argue that the discrimination and cruelty humans project towards other humans mirrors the discrimination and cruelty humans project towards other species.
Anwarzai, Farhad R.
core +1 more source
A Moorean argument for the full moral status of those with profound intellectual disability [PDF]
, 2015 This paper is about the moral status of those human beings with profound intellectual disabilities (PIDs). We hold the common sense view that they have equal status to 'normal' human beings, and a higher status than any non-human animal.
Curtis, B, Vehmas, S
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
, 1987 Material appearing below is thought to be of particular interest to Linacre Quarterly readers because of its moral, religious, or philosophic content. The medical literature constitutes the primary, but not the sole source of such material.
Catholic Physicians\u27 Guild
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Doing the Right Thing: An Interview With Stevan Harnad [PDF]
, 2015 Twelve years after stepping down from the editorship of BBS I have accepted an invitation from the Humane Society of the United States to serve as editor in chief of Animal Sentience, a new journal just about to be launched that is devoted to ...
Bekoff, Marc, Harnad, Stevan
core
, 2016 Recent research and theorizing suggest that desires for group–based dominance underpin biases towards both human outgroups and (non–human) animals. A systematic study of the common ideological roots of human–human and human–animal biases is, however ...
Kristof Dhont +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source