Results 101 to 110 of about 533,212 (256)

Beyond the dualism between domain-general and domain-specific abilities: a developmental approach to mathematical learning

open access: yesFrontiers in Developmental Psychology
Understanding how cognitive abilities support mathematical learning across development remains a central question in psychology. Traditionally, scietific literature has distinguished between domain-specific abilities, referring to processes specifically ...
Gisella Decarli, Gisella Decarli
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

DIFFERENCES BETWEEN CADET AND YOUNGER CADET HANDBALL PLAYERS IN SPECIFIC MOTOR ABILITIES [PDF]

open access: yesSport Mont, 2012
The differences were analyzed between 12 cadet and 12 younger cadet handball players in indicators of specific motor abilities. Central and dispersive parameters were computed of the variables obtained in the testing procedures.
Dinko Vuleta   +2 more
doaj  

Analysis of general and specific combining abilities of popcorn populations, including selfed parents

open access: yesGenetics and Molecular Biology, 2003
Estimation of general and specific combining ability effects in a diallel analysis of cross-pollinating populations, including the selfed parents, is presented in this work.
José Marcelo Soriano Viana   +1 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Testing specific cognitive abilities by telephone and mail

open access: yes, 1987
The two goals of this research were to develop a brief battery of tests of specific cognitive abilities that can be administered via telephone to adolescents and to assess the psychometric properties of the battery. In a sample of 212 adolescents from 10
Kent, Jaylene, Plomin, Robert
core   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

How Does Processing Affect Storage in Working Memory Tasks? Evidence for Both Domain-General and Domain-Specific Effects

open access: yes, 2011
Two studies that examine whether the forgetting caused by the processing demands of working memory tasks is domain-general or domain-specific are presented. In each, separate groups of adult participants were asked to carry out either verbal or nonverbal
Harvey, Caroline E.   +7 more
core   +1 more source

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