Results 201 to 210 of about 17,312,941 (313)

Improvement of optimum pH and specific activity of pectate lyase from Bacillus RN.1 using loop replacement. [PDF]

Front Bioeng Biotechnol, 2023
Li P, Wei X, Wang Y, Liu H, Xu Y, Zhang Z, Li J, Wang J, Guo C, Sui S, Wang J, Wang R.   +11 more
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Multiple rotavirus species encode fusion-associated small transmembrane (FAST) proteins with cell type-specific activity. [PDF]

J Virol
Sartalamacchia K, Veletanlic V, Diller JR, Ogden KM.   +3 more
europepmc   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

A Novel Cobalt-Activated Halotolerant α-Amylase with High Specific Activity from <i>Priestia</i> sp. W243 in Kuwait Sabkha for Biotechnological Applications. [PDF]

Mar Drugs
Alagarsamy S, Habeebullah SFK, Azad IS, Fakhraldeen SA, Al Said T, Al Ghuniam A, Al-Yamani F.   +6 more
europepmc   +1 more source

Novel specific activity-based probes validate KLK proteases as druggable targets. [PDF]

Cancer Biol Ther, 2022
Sotiropoulou G, Zingkou E, Pampalakis G.
europepmc   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Correction for Zhao et al., "A novel phage putative depolymerase, Depo16, has specific activity against K1 capsular-type Klebsiella pneumoniae". [PDF]

Appl Environ Microbiol
Zhao R, Jiang S, Ren S, Yang L, Han W, Guo Z, Gu J.   +6 more
europepmc   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Phage vB_KpnM_JYSS3 encodes a novel polysaccharide depolymerase that exhibits specific activity against K2-type carbapenem-resistant Klebsiella pneumoniae. [PDF]

BMC Microbiol
Jiao SY, Wang X, Wang J, Liu YY, Zhang L, Peng XC, Song JL, Wang CM, Zhang W, Li XJ.   +9 more
europepmc   +1 more source