Results 181 to 190 of about 17,312,941 (313)

Trading specific activity for productivity [PDF]

Biotechnology and Bioengineering, 2017
openaire   +2 more sources

Assessment of biotechnological products specific activity

, 2018
The review looks into various aspects of assessing specific activity of biotechnological products, which is one of their key quality parameters. Approaches to the analysis of this parameter and the choice of test procedures are governed by the nature and
E. V. Motuzova, A. K. Yakovlev, Zh. I. Avdeeva, N. A. Alpatova, L. A. Gayderova, S. L. Lysikova, A. A. Soldatov   +6 more
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

A semi-solid in vitro biofilm model for evaluating antimicrobial potency and biofilm-specific activity. [PDF]

Biofilm
Fuglsang-Madsen A, Kvich LA, Henriksen NL, Kristensen R, Henriksen JR, Hansen AE, Bjarnsholt T, Jakobsen TH.   +7 more
europepmc   +1 more source

Assessing Local and Branch-specific Activity in Dendrites. [PDF]

Neuroscience, 2022
Moore JJ, Robert V, Rashid SK, Basu J.
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

CAR-T cells directed toward PD-L1 demonstrate potent, antigen-specific activity against cholangiocarcinoma: A proof of concept study. [PDF]

Mol Ther Oncol
Gondaliya P, Luo Y, Sayyed AA, Zinn DA, Qie Y, Yan IK, Driscoll J, Patel PB, Li S, Qin H, Patel T.   +10 more
europepmc   +1 more source

Site-Specific Activity-Based Protein Profiling Using Phosphonate Handles. [PDF]

Mol Cell Proteomics, 2023
van Bergen W, Hevler JF, Wu W, Baggelaar MP, Heck AJR.   +4 more
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

RelabotulinumtoxinA, a Ready-to-Use Formulation Neuromodulator Manufactured with PEARL™ Technology to Maintain High Biological and Specific Activity. [PDF]

Toxins (Basel)
Ståhl U, Lekholm E, Hamnevik E, Fredriksson R, Shridharani SM, Taghetchian K, Cohen JL, Nestor MS, Liljegren Sundberg Å.   +8 more
europepmc   +1 more source