Results 171 to 180 of about 17,312,941 (313)

Improving fMRI in Parkinson's disease by accounting for brain region-specific activity patterns. [PDF]

Neuroimage Clin, 2023
Torrecuso R, Mueller K, Holiga Š, Sieger T, Vymazal J, Ružička F, Roth J, Ružička E, Schroeter ML, Jech R, Möller HE.   +10 more
europepmc   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

A case of protein S-specific activity triggers detection with potential thrombosis development. [PDF]

J Vasc Surg Cases Innov Tech
Yamada H, Ohgi M, Tominaga N, Tsujimoto A, Fujishima A, Matsumoto S.   +5 more
europepmc   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Dual human lung models reveal compartment-specific activity of anti-tuberculosis drugs and host-directed therapies. [PDF]

Microbiol Spectr
Barbosa Bomfim CC, Faivre N, Benoist T, Popis M, Suire B, Pericat D, Sánchez-López JM, Aponte-Castillo BM, Näser E, Viana P, Guibert N, Vergé R, Mazières J, Métais A, Poincloux R, Raynaud-Messina B, Dumas F, Neyrolles O, Vérollet C, Meunier E, Lugo-Villarino G, Cougoule C.   +21 more
europepmc   +1 more source

Expectation Cues and False Percepts Generate Stimulus-Specific Activity in Distinct Layers of the Early Visual Cortex. [PDF]

J Neurosci, 2023
Haarsma J, Deveci N, Corbin N, Callaghan MF, Kok P.   +4 more
europepmc   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Oncolytic vaccinia virus JX-594 shows subtype-specific activity and candidate biomarkers in gastric cancer cell lines. [PDF]

Sci Rep
Kim JH, Kim Y, Shin Y, Park I, Kwon WS, Kim TS, Lee N, Oh K, Kim C, Jeung HC, Rha SY.   +10 more
europepmc   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Smooth Muscle Cell Specific Activity of SGK-1 Alters Aortic Stiffness and Abdominal Aortic Aneurysm Growth. [PDF]

J Vasc Dis
Anderson M, Zhang L, Figueroa M, Mattia V, Rovner A, Uppalapati V, Xiong Y, Mukherjee R, Jones JA, Ruddy JM.   +9 more
europepmc   +1 more source